(40 nodes) Germ cell nucleus network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Blm	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (464 aa)
	I79_026256	Spliceosome RNA helicase Bat1. (103 aa)
	I79_025858	Spliceosome RNA helicase BAT1. (66 aa)
	I79_025672	Spliceosome RNA helicase BAT1. (155 aa)
	I79_025570	Spliceosome RNA helicase Bat1. (229 aa)
	Trip13	Thyroid receptor-interacting protein 13; Belongs to the AAA ATPase family. (404 aa)
	I79_024008	High mobility group nucleosome-binding domain-containing protein 4. (89 aa)
	I79_023244	Bloom syndrome protein-like. (721 aa)
	I79_020102	Histone H2A; Belongs to the histone H2A family. (143 aa)
	CgPICR_014164	High mobility group nucleosome-binding domain-containing protein 4. (90 aa)
	I79_018989	High mobility group nucleosome-binding domain-containing protein 4. (83 aa)
	Stag3	Cohesin subunit SA-3. (1032 aa)
	I79_018706	Cohesin subunit SA-3. (669 aa)
	Ddx39b	Spliceosome RNA helicase BAT1. (288 aa)
	I79_016123	Ret finger protein-like 4A. (238 aa)
	I79_015018	Histone H1oo. (285 aa)
	Mlh1	DNA mismatch repair protein Mlh1-like protein. (720 aa)
	I79_012829	Histone H2A; Belongs to the histone H2A family. (146 aa)
	I79_012393	Zinc finger protein 60. (209 aa)
	I79_012392	Zinc finger protein 60. (950 aa)
	I79_012390	Zinc finger protein 780B. (745 aa)
	Stpg1	UPF0490 protein C1orf201-like. (213 aa)
	Limk1	LIM domain kinase 1. (283 aa)
	I79_011106	Non-histone chromosomal protein HMG-17. (109 aa)
	I79_010912	Spermatid-specific linker histone H1-like protein. (174 aa)
	Actrt3	Actin-related protein M1-like. (99 aa)
	Mlh3	Acylphosphatase. (1533 aa)
	I79_008544	Meiotic recombination protein REC8-like. (451 aa)
	Aurka	Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (386 aa)
	Actl7a	Actin-like protein 7A; Belongs to the actin family. (440 aa)
	I79_006262	MORC family CW-type zinc finger protein 1. (291 aa)
	I79_005272	Transcription initiation factor TFIID subunit 7-like. (384 aa)
	Tnp1	Spermatid nuclear transition protein 1. (109 aa)
	Topbp1	DNA topoisomerase II-binding protein 1. (1517 aa)
	Csnka2ip	Uncharacterized protein. (729 aa)
	I79_002788	Zinc finger MYND domain-containing protein 15. (494 aa)
	I79_002659	High mobility group protein HMGI-C. (103 aa)
	Lhx8	LIM/homeobox protein Lhx8. (230 aa)
	I79_001484	65 kDa Yes-associated protein. (257 aa)
	Ncapd3	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1096 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aurka	Ncapd3	G3HBL6	G3GTW0	Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily.	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.	0.436
Aurka	Trip13	G3HBL6	G3ILQ1	Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily.	Thyroid receptor-interacting protein 13; Belongs to the AAA ATPase family.	0.568
Blm	I79_012829	G3IG14	G3HPV8	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	Histone H2A; Belongs to the histone H2A family.	0.414
Blm	I79_020102	G3IG14	G3I968	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	Histone H2A; Belongs to the histone H2A family.	0.414
Blm	I79_023244	G3IG14	G3IHF5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	Bloom syndrome protein-like.	0.854
Blm	Mlh1	G3IG14	G3HTA5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	DNA mismatch repair protein Mlh1-like protein.	0.918
Blm	Mlh3	G3IG14	G3HFQ8	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	Acylphosphatase.	0.575
Blm	Topbp1	G3IG14	G3GZG7	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	DNA topoisomerase II-binding protein 1.	0.819
I79_002788	Tnp1	G3GYB3	G3H3Z8	Zinc finger MYND domain-containing protein 15.	Spermatid nuclear transition protein 1.	0.429
I79_008544	I79_018706	G3HDD9	G3I5G0	Meiotic recombination protein REC8-like.	Cohesin subunit SA-3.	0.887
I79_008544	Mlh1	G3HDD9	G3HTA5	Meiotic recombination protein REC8-like.	DNA mismatch repair protein Mlh1-like protein.	0.497
I79_008544	Mlh3	G3HDD9	G3HFQ8	Meiotic recombination protein REC8-like.	Acylphosphatase.	0.428
I79_008544	Stag3	G3HDD9	G3I5G1	Meiotic recombination protein REC8-like.	Cohesin subunit SA-3.	0.887
I79_008544	Trip13	G3HDD9	G3ILQ1	Meiotic recombination protein REC8-like.	Thyroid receptor-interacting protein 13; Belongs to the AAA ATPase family.	0.521
I79_010912	I79_015018	G3HJR3	G3HVM0	Spermatid-specific linker histone H1-like protein.	Histone H1oo.	0.480
I79_011106	I79_018989	G3HK88	G3I677	Non-histone chromosomal protein HMG-17.	High mobility group nucleosome-binding domain-containing protein 4.	0.419
I79_012829	Blm	G3HPV8	G3IG14	Histone H2A; Belongs to the histone H2A family.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.414
I79_012829	I79_023244	G3HPV8	G3IHF5	Histone H2A; Belongs to the histone H2A family.	Bloom syndrome protein-like.	0.414
I79_015018	I79_010912	G3HVM0	G3HJR3	Histone H1oo.	Spermatid-specific linker histone H1-like protein.	0.480
I79_018706	I79_008544	G3I5G0	G3HDD9	Cohesin subunit SA-3.	Meiotic recombination protein REC8-like.	0.887