STRINGSTRING
I79_001957 I79_001957 I79_002246 I79_002246 Creld1 Creld1 I79_013535 I79_013535 I79_013556 I79_013556 H671_5g13763 H671_5g13763 Creld2 Creld2 Acan Acan Nell2 Nell2 I79_003394 I79_003394 I79_021564 I79_021564 I79_022092 I79_022092 I79_013621 I79_013621 I79_014532 I79_014532 Ccbe1 Ccbe1 I79_015126 I79_015126 I79_003408 I79_003408 Crtac1 Crtac1 I79_003452 I79_003452 I79_003637 I79_003637 I79_015127 I79_015127 Fat1 Fat1 Lrp1 Lrp1 I79_015624 I79_015624 I79_015855 I79_015855 Dlk2 Dlk2 Gpsm3 Gpsm3 Tmem145 Tmem145 Efemp2 Efemp2 Wrap73 Wrap73 I79_022667 I79_022667 I79_022671 I79_022671 I79_023010 I79_023010 I79_024292 I79_024292 I79_008232 I79_008232 Pkn1 Pkn1 I79_009100 I79_009100 I79_010173 I79_010173 I79_011076 I79_011076 Fat4 Fat4 I79_017864 I79_017864 Vcan Vcan I79_011219 I79_011219 Umodl1 Umodl1 I79_011565 I79_011565 Crb1 Crb1 I79_011804 I79_011804 Cd93 Cd93 Shkbp1 Shkbp1 Dll1 Dll1 Notch2 Notch2 NOTCH1 NOTCH1 I79_000317 I79_000317 Jag1 Jag1 I79_000871 I79_000871 I79_001015 I79_001015 I79_001239 I79_001239 C1s C1s C1r C1r Sftpc Sftpc I79_004721 I79_004721 Ncan Ncan I79_007806 I79_007806 Thbs3 Thbs3 I79_024611 I79_024611 Umod Umod I79_025170 I79_025170 LDLR LDLR Gas6 Gas6 I79_020072 I79_020072 I79_020073 I79_020073 I79_020218 I79_020218 I79_020269 I79_020269
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_001957Slit-like 3 protein. (751 aa)
I79_002246Hemicentin-1. (1801 aa)
Creld1Cysteine-rich with EGF-like domain protein 1. (420 aa)
I79_013535Fibrillin-3. (1889 aa)
I79_013556Fibrillin-1. (2698 aa)
H671_5g13763EGF-like module-containing mucin-like hormone receptor-like 4; Belongs to the G-protein coupled receptor 2 family. (487 aa)
Creld2Cysteine-rich with EGF-like domain protein 2. (308 aa)
AcanAggrecan core protein. (2120 aa)
Nell2Protein kinase C-binding protein NELL2. (274 aa)
I79_003394Metalloendopeptidase. (995 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
I79_022092Mannan-binding lectin serine protease 2. (185 aa)
I79_013621Signal peptide, CUB and EGF-like domain-containing protein 3. (855 aa)
I79_014532Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1. (2987 aa)
Ccbe1Collagen and calcium-binding EGF domain-containing protein 1. (303 aa)
I79_015126Multiple epidermal growth factor-like domains 6. (109 aa)
I79_003408Slit-like 1 protein. (1482 aa)
Crtac1Cartilage acidic protein 1. (681 aa)
I79_003452Fibulin-7. (766 aa)
I79_003637Low-density lipoprotein receptor-related protein 4. (766 aa)
I79_015127EGF-like domain-containing protein C3orf50-like. (339 aa)
Fat1Protocadherin Fat 1. (4589 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
I79_015624Thrombospondin-4. (960 aa)
I79_015855Signal peptide, CUB and EGF-like domain-containing protein 1. (773 aa)
Dlk2Protein delta-like 2. (382 aa)
Gpsm3Neurogenic locus notch-like protein 4. (1797 aa)
Tmem145Multiple epidermal growth factor-like domains 8. (2639 aa)
Efemp2EGF-containing fibulin-like extracellular matrix protein 2. (375 aa)
Wrap73Multiple epidermal growth factor-like domains 6. (1488 aa)
I79_022667Fibulin-1. (628 aa)
I79_022671Delta and Notch-like epidermal growth factor-related receptor. (176 aa)
I79_023010Latent-transforming growth factor beta-binding protein 3. (624 aa)
I79_024292EGF-like domain-containing protein 7. (238 aa)
I79_008232EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family. (944 aa)
Pkn1Serine/threonine-protein kinase N1; Belongs to the G-protein coupled receptor 2 family. (1696 aa)
I79_009100Latent-transforming growth factor beta-binding protein 1. (1194 aa)
I79_010173Cubilin. (1951 aa)
I79_011076Coagulation factor X. (629 aa)
Fat4Protocadherin Fat 4. (5152 aa)
I79_017864Fibrillin-2. (2601 aa)
VcanUncharacterized protein. (607 aa)
I79_011219Vitamin K-dependent protein C. (381 aa)
Umodl1Uromodulin-like 1. (1351 aa)
I79_011565Crumbs-like 2. (1065 aa)
Crb1Crumbs-like 1. (989 aa)
I79_011804Neurogenic locus notch-like protein 3. (2181 aa)
Cd93Complement component C1q receptor. (811 aa)
Shkbp1SH3KBP1-binding protein 1. (1696 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
NOTCH1Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2527 aa)
I79_000317Fibulin-2. (1193 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
I79_000871Mannan-binding lectin serine protease 1; Belongs to the peptidase S1 family. (706 aa)
I79_001015Low-density lipoprotein receptor-related protein 8. (764 aa)
I79_001239Low-density lipoprotein receptor-related protein 2. (4664 aa)
C1sCalcium-dependent serine proteinase; Belongs to the peptidase S1 family. (695 aa)
C1rComplement C1r-A subcomponent; Belongs to the peptidase S1 family. (705 aa)
SftpcMetalloendopeptidase. (1019 aa)
I79_004721Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa)
NcanNeurocan core protein. (1234 aa)
I79_007806Thyroid peroxidase. (841 aa)
Thbs3Thrombospondin-3. (956 aa)
I79_024611Signal peptide, CUB and EGF-like domain-containing protein 2. (583 aa)
UmodUromodulin. (618 aa)
I79_025170Slit-like 2 protein. (345 aa)
LDLRLow-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
Gas6Growth arrest-specific protein 6. (684 aa)
I79_020072Latent-transforming growth factor beta-binding protein 2. (52 aa)
I79_020073Latent-transforming growth factor beta-binding protein 2. (286 aa)
I79_020218Protein kinase C-binding protein NELL2. (452 aa)
I79_020269EGF-containing fibulin-like extracellular matrix protein 1. (438 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.