STRINGSTRING
Tlr9 Tlr9 Pik3r1 Pik3r1 I79_006679 I79_006679 I79_008814 I79_008814 Fgf1 Fgf1 I79_008997 I79_008997 I79_009115 I79_009115 I79_009116 I79_009116 Fgf22 Fgf22 I79_010199 I79_010199 Fgf20 Fgf20 Spem1 Spem1 Spem2 Spem2 I79_002104 I79_002104 I79_001940 I79_001940 I79_010317 I79_010317 I79_010890 I79_010890 Fgfr3 Fgfr3 I79_011625 I79_011625 Kl Kl Akt2 Akt2 I79_024980 I79_024980 H671_6g15462 H671_6g15462 Fgf16 Fgf16 I79_013529 I79_013529 I79_013530 I79_013530 CgPICR_020133 CgPICR_020133 H671_7g17291 H671_7g17291 I79_013773 I79_013773 I79_013974 I79_013974 I79_015257 I79_015257 Pik3c3 Pik3c3 Npm3 Npm3 Frs2 Frs2 Flt3lg Flt3lg Pik3ca Pik3ca H671_1g1070 H671_1g1070 Kctd5 Kctd5 I79_017790 I79_017790 Fgf3 Fgf3 Fgf4 Fgf4 Fgf19 Fgf19 CgPICR_017317 CgPICR_017317 I79_025089 I79_025089 I79_025528 I79_025528 I79_025563 I79_025563 I79_025621 I79_025621 I79_025973 I79_025973 I79_019065 I79_019065 I79_019131 I79_019131 I79_019149 I79_019149 I79_019326 I79_019326 I79_001850 I79_001850 Fgf17 Fgf17 I79_001364 I79_001364 Fgf23 Fgf23 CgPICR_003432 CgPICR_003432 CgPICR_012052 CgPICR_012052 CgPICR_008423 CgPICR_008423 Trib3 Trib3 I79_000590 I79_000590 I79_000583 I79_000583 Fgf7 Fgf7 I79_020792 I79_020792 Gab2 Gab2 I79_020968 I79_020968 I79_020969 I79_020969 I79_021408 I79_021408 CgPICR_007800 CgPICR_007800 Irs1 Irs1 I79_024014 I79_024014 I79_024157 I79_024157 Fgfr2 Fgfr2 I79_024224 I79_024224 Irs2 Irs2 Klb Klb I79_005111 I79_005111 I79_004979 I79_004979 I79_004244 I79_004244 I79_004031 I79_004031 I79_003906 I79_003906 I79_003250 I79_003250 Pik3r4 Pik3r4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tlr9Toll-like receptor 9. (1239 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
I79_006679Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
I79_008814GRB2-associated-binding protein 2. (88 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
I79_008997GRB2-associated-binding protein 2. (265 aa)
I79_009115Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (441 aa)
I79_009116Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (311 aa)
Fgf22Fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (70 aa)
I79_010199GRB2-associated-binding protein 2. (173 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
Spem1Spermatid maturation protein 1. (311 aa)
Spem2Uncharacterized protein C17orf74-like; Belongs to the heparin-binding growth factors family. (979 aa)
I79_002104FL cytokine receptor. (890 aa)
I79_001940GRB2-associated-binding protein 2. (135 aa)
I79_010317GRB2-associated-binding protein 2. (234 aa)
I79_010890GRB2-associated-binding protein 2. (92 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
I79_011625GRB2-associated-binding protein 2. (115 aa)
KlKlotho. (900 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
I79_024980GRB2-associated-binding protein 2. (88 aa)
H671_6g15462GRB2-associated-binding protein 2. (144 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
I79_013529GRB2-associated-binding protein 2. (114 aa)
I79_013530GRB2-associated-binding protein 2. (156 aa)
CgPICR_020133GRB2-associated-binding protein 2. (360 aa)
H671_7g17291GRB2-associated-binding protein 2. (86 aa)
I79_013773cGMP-inhibited 3',5'-cyclic phosphodiesterase B. (265 aa)
I79_013974GRB2-associated-binding protein 2. (173 aa)
I79_015257GRB2-associated-binding protein 2. (138 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (822 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
Flt3lgSL cytokine. (230 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
H671_1g1070Fibroblast growth factor 5-like protein; Belongs to the heparin-binding growth factors family. (239 aa)
Kctd53-phosphoinositide-dependent protein kinase 1; Belongs to the peptidase S1 family. (799 aa)
I79_017790GRB2-associated-binding protein 2. (154 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
CgPICR_017317Insulin receptor substrate 1. (493 aa)
I79_025089GRB2-associated-binding protein 2. (517 aa)
I79_025528GRB2-associated-binding protein 2. (137 aa)
I79_025563GRB2-associated-binding protein 2. (142 aa)
I79_025621GRB2-associated-binding protein 2. (367 aa)
I79_025973GRB2-associated-binding protein 2. (116 aa)
I79_019065GRB2-associated-binding protein 2. (142 aa)
I79_019131GRB2-associated-binding protein 2. (83 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
I79_019326GRB2-associated-binding protein 2. (159 aa)
I79_001850GRB2-associated-binding protein 2. (142 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (350 aa)
I79_001364Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
CgPICR_003432GRB2-associated-binding protein 2. (186 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
CgPICR_008423GRB2-associated-binding protein 2. (103 aa)
Trib3Tribbles-like 3. (353 aa)
I79_000590GRB2-associated-binding protein 2. (197 aa)
I79_000583GRB2-associated-binding protein 2. (123 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
I79_020792GRB2-associated-binding protein 2. (133 aa)
Gab2GRB2-associated-binding protein 2. (485 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
I79_020969Fibroblast growth factor 18. (85 aa)
I79_021408GRB2-associated-binding protein 2. (129 aa)
CgPICR_007800GRB2-associated-binding protein 2. (126 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_024014GRB2-associated-binding protein 2. (137 aa)
I79_024157GRB2-associated-binding protein 2. (161 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_024224GRB2-associated-binding protein 2. (117 aa)
Irs2Insulin receptor substrate 2. (465 aa)
KlbBeta-klotho; Belongs to the glycosyl hydrolase 1 family. (730 aa)
I79_005111Phosphatidylinositol 3-kinase regulatory subunit beta. (653 aa)
I79_004979GRB2-associated-binding protein 2. (97 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
I79_004031Fibroblast growth factor receptor. (731 aa)
I79_003906Fibroblast growth factor receptor 4. (1040 aa)
I79_003250Phosphoinositide 3-kinase regulatory subunit 4. (194 aa)
Pik3r4Phosphoinositide 3-kinase regulatory subunit 4. (993 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (22%) [HD]