STRINGSTRING
I79_021535 I79_021535 I79_000224 I79_000224 I79_000303 I79_000303 Umps Umps Dctd Dctd Gart Gart Nt5e Nt5e I79_000934 I79_000934 I79_001116 I79_001116 Gmpr Gmpr Nudt18 Nudt18 Entpd4 Entpd4 Nudt1 Nudt1 Nudt5 Nudt5 I79_001838 I79_001838 Adk Adk I79_002513 I79_002513 Cad Cad Samhd1 Samhd1 Pfas Pfas Adprm Adprm IMPDH IMPDH CgPICR_013214 CgPICR_013214 Entpd1 Entpd1 I79_003387 I79_003387 Adal Adal Gmps Gmps Tk1 Tk1 ITPA ITPA Slc25a42 Slc25a42 Papolg Papolg I79_005323 I79_005323 I79_005344 I79_005344 Gsr Gsr Tk2 Tk2 I79_006119 I79_006119 I79_006155 I79_006155 Glrx Glrx Adss2 Adss2 Cdadc1 Cdadc1 Ak2 Ak2 Dhodh Dhodh Cmpk2 Cmpk2 H671_7g18194 H671_7g18194 CgPICR_020542 CgPICR_020542 Nme3 Nme3 I79_007877 I79_007877 I79_008219 I79_008219 Ctps1 Ctps1 GMPR GMPR I79_009122 I79_009122 Ipo13 Ipo13 Hprt1 Hprt1 I79_009773 I79_009773 I79_009898 I79_009898 Uckl1 Uckl1 I79_010033 I79_010033 I79_010131 I79_010131 I79_010150 I79_010150 Upp2 Upp2 Pudp Pudp Nt5dc1 Nt5dc1 Rrm2b Rrm2b Ada Ada Nt5c3a Nt5c3a Nt5c1a Nt5c1a Entpd5 Entpd5 Uck2 Uck2 I79_012910 I79_012910 IL12A IL12A I79_013073 I79_013073 I79_013121 I79_013121 Smim3 Smim3 Nudt16l1 Nudt16l1 Nudt6 Nudt6 Glrx2 Glrx2 Ak1 Ak1 I79_014944 I79_014944 I79_015041 I79_015041 Adsl Adsl I79_015701 I79_015701 Upb1 Upb1 Ak4 Ak4 Ampd3 Ampd3 DNPH1 DNPH1 I79_016330 I79_016330 Nudt15 Nudt15 Cep44 Cep44 I79_017168 I79_017168 H671_1g1582 H671_1g1582 Pnp Pnp Atic Atic Ctps2 Ctps2 I79_017541 I79_017541 Rrm2 Rrm2 Nudt13 Nudt13 I79_017784 I79_017784 Rrm1 Rrm1 I79_018279 I79_018279 Dck Dck Xdh Xdh I79_018438 I79_018438 I79_018891 I79_018891 Entpd8 Entpd8 I79_018919 I79_018919 Ampd2 Ampd2 I79_020339 I79_020339 Upp1 Upp1 Nrsn1 Nrsn1 Dpyd Dpyd Qrich1 Qrich1 Dalrd3 Dalrd3 Entpd7 Entpd7 Enkur Enkur Ak8 Ak8 Ppat Ppat Paics Paics I79_022567 I79_022567 Tyms Tyms Nt5c2 Nt5c2 I79_023016 I79_023016 Gda Gda Nudt9 Nudt9 I79_023713 I79_023713 Entpd2 Entpd2 Dctpp1 Dctpp1 I79_025317 I79_025317 I79_025923 I79_025923 IMPDH2 IMPDH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_021535Phosphoribosyltransferase domain-containing protein 1. (80 aa)
I79_000224Adenine phosphoribosyltransferase. (192 aa)
I79_000303Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (385 aa)
UmpsUridine 5'-monophosphate synthase. (480 aa)
DctdDeoxycytidylate deaminase. (178 aa)
GartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
Nt5e5'-nucleotidase; Belongs to the 5'-nucleotidase family. (556 aa)
I79_0009345'(3')-deoxyribonucleotidase, cytosolic type. (236 aa)
I79_001116Thymidine kinase. (122 aa)
GmprGMP reductase 1. (106 aa)
Nudt18Nucleoside diphosphate-linked moiety X motif 18; Belongs to the Nudix hydrolase family. (323 aa)
Entpd4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (487 aa)
Nudt17,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. (131 aa)
Nudt5ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family. (216 aa)
I79_001838Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (466 aa)
AdkAdenosine kinase. (361 aa)
I79_002513Uncharacterized protein C6orf224. (1162 aa)
CadCAD protein. (2225 aa)
Samhd1SAM domain and HD domain-containing protein 1. (670 aa)
PfasPhosphoribosylformylglycinamidine synthase. (1338 aa)
AdprmManganese-dependent ADP-ribose/CDP-alcohol diphosphatase. (260 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (437 aa)
CgPICR_013214U8 snoRNA-decapping enzyme. (181 aa)
Entpd1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (269 aa)
I79_003387Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (219 aa)
AdalAdenosine deaminase-like protein. (355 aa)
GmpsGMP synthase [glutamine-hydrolyzing]. (1159 aa)
Tk1Thymidine kinase. (234 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (196 aa)
Slc25a42Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. (89 aa)
PapolgPoly(A) polymerase gamma. (709 aa)
I79_005323Thymidylate kinase. (75 aa)
I79_005344Adenylate kinase isoenzyme 4, mitochondrial. (106 aa)
GsrGlutathione reductase, mitochondrial. (410 aa)
Tk2Thymidine kinase 2, mitochondrial. (264 aa)
I79_006119Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (202 aa)
I79_006155Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (146 aa)
GlrxGlutaredoxin-1. (106 aa)
Adss2Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (355 aa)
Cdadc1Cytidine and dCMP deaminase domain-containing protein 1. (522 aa)
Ak2Adenylate kinase 2, mitochondrial; Belongs to the adenylate kinase family. (142 aa)
DhodhDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
Cmpk2UMP-CMP kinase 2, mitochondrial. (223 aa)
H671_7g18194Nucleoside diphosphate kinase. (152 aa)
CgPICR_020542Nucleoside diphosphate kinase. (152 aa)
Nme3Nucleoside diphosphate kinase. (169 aa)
I79_007877Nucleoside diphosphate kinase. (228 aa)
I79_008219Adenylate kinase isoenzyme 1; Belongs to the adenylate kinase family. (200 aa)
Ctps1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa)
I79_009122Thioredoxin domain-containing protein 6. (237 aa)
Ipo13Importin-13. (963 aa)
Hprt1Hypoxanthine-guanine phosphoribosyltransferase. (76 aa)
I79_009773Cytosolic 5'-nucleotidase 1B. (632 aa)
I79_009898Uridine-cytidine kinase-like 1. (213 aa)
Uckl1Uridine-cytidine kinase; Belongs to the uridine kinase family. (334 aa)
I79_010033Putative adenylate kinase 7. (648 aa)
I79_010131Guanylate kinase. (210 aa)
I79_0101505'(3')-deoxyribonucleotidase, mitochondrial. (66 aa)
Upp2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (250 aa)
PudpHaloacid dehalogenase-like hydrolase domain-containing protein 1A. (229 aa)
Nt5dc15'-nucleotidase domain-containing protein 1. (443 aa)
Rrm2bRibonucleoside-diphosphate reductase subunit M2 B. (114 aa)
AdaAdenosine deaminase. (363 aa)
Nt5c3a5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (308 aa)
Nt5c1aCytosolic 5'-nucleotidase 1A. (365 aa)
Entpd5Ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. (453 aa)
Uck2Uridine-cytidine kinase 2. (235 aa)
I79_012910Schwannomin-interacting protein 1. (156 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
I79_013073AMP deaminase 1. (78 aa)
I79_013121Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (565 aa)
Smim3Putative small membrane protein NID67. (60 aa)
Nudt16l1Protein syndesmos. (237 aa)
Nudt6Nucleoside diphosphate-linked moiety X motif 6; Belongs to the Nudix hydrolase family. (322 aa)
Glrx2Glutaredoxin-2, mitochondrial. (83 aa)
Ak1Adenylate kinase isoenzyme 1; Belongs to the adenylate kinase family. (54 aa)
I79_014944Dihydropyrimidinase. (304 aa)
I79_015041Thymidylate synthase. (192 aa)
AdslAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (484 aa)
I79_015701CTP synthase 2. (185 aa)
Upb1Beta-ureidopropionase. (393 aa)
Ak4Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (161 aa)
Ampd3AMP deaminase 3. (102 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (163 aa)
I79_016330Thioredoxin domain-containing protein 2. (553 aa)
Nudt15Putative 7,8-dihydro-8-oxoguanine triphosphatase NUDT15. (184 aa)
Cep44Uncharacterized protein KIAA1712-like. (368 aa)
I79_0171685_nucleotid_C domain-containing protein. (240 aa)
H671_1g1582Ribonucleoside-diphosphate reductase subunit M2-like protein. (96 aa)
PnpPurine nucleoside phosphorylase. (283 aa)
AticBifunctional purine biosynthesis protein PURH. (592 aa)
Ctps2CTP synthase 2. (362 aa)
I79_017541Uridine-cytidine kinase 1. (178 aa)
Rrm2Ribonucleoside-diphosphate reductase subunit M2. (390 aa)
Nudt13Nucleoside diphosphate-linked moiety X motif 13. (226 aa)
I79_017784Dihydropyrimidine dehydrogenase [NADP+]. (519 aa)
Rrm1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
I79_018279Deoxyguanosine kinase, mitochondrial. (216 aa)
DckDeoxycytidine kinase. (260 aa)
XdhXanthine dehydrogenase/oxidase. (1332 aa)
I79_018438Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (202 aa)
I79_018891Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (322 aa)
Entpd8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (466 aa)
I79_018919Haloacid dehalogenase-like hydrolase domain-containing protein 1A. (132 aa)
Ampd2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (798 aa)
I79_020339Guanine deaminase. (70 aa)
Upp1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (282 aa)
Nrsn1Neurensin-1-like protein. (195 aa)
DpydDihydropyrimidine dehydrogenase [NADP+]. (74 aa)
Qrich1Glutamine-rich protein 1. (777 aa)
Dalrd3DALR anticodon-binding domain-containing protein 3. (458 aa)
Entpd7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (558 aa)
EnkurEnkurin. (186 aa)
Ak8Putative adenylate kinase-like protein C9orf98-like; Belongs to the adenylate kinase family. (374 aa)
PpatAmidophosphoribosyltransferase. (251 aa)
PaicsMultifunctional protein ADE2. (87 aa)
I79_022567Amidophosphoribosyltransferase. (90 aa)
TymsThymidylate synthase-like protein. (307 aa)
Nt5c2Cytosolic purine 5'-nucleotidase. (560 aa)
I79_023016Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (250 aa)
GdaGuanine deaminase. (213 aa)
Nudt9ADP-ribose pyrophosphatase, mitochondrial. (350 aa)
I79_023713Dihydropyrimidine dehydrogenase [NADP+]. (120 aa)
Entpd2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (485 aa)
Dctpp1dCTP pyrophosphatase 1. (157 aa)
I79_025317Putative adenylate kinase-like protein C9orf98-like. (114 aa)
I79_025923Adenylate kinase 2, mitochondrial; Belongs to the adenylate kinase family. (77 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. Belongs to the IMPDH/GMPR family. (514 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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