STRINGSTRING
Crtc3 Crtc3 I79_026075 I79_026075 ATP8 ATP8 ATP6 ATP6 I79_000004 I79_000004 Chchd6 Chchd6 Atp5po Atp5po Atp5pd Atp5pd C7H17orf80 C7H17orf80 SIRT4 SIRT4 I79_001600 I79_001600 Tmem11 Tmem11 I79_003030 I79_003030 Nrf1 Nrf1 I79_003341 I79_003341 Gabpb1 Gabpb1 SIRT5 SIRT5 Mtx2 Mtx2 Atp5mc3 Atp5mc3 I79_004417 I79_004417 I79_004557 I79_004557 Gabpb2 Gabpb2 Crtc1 Crtc1 I79_006001 I79_006001 I79_007391 I79_007391 Atp5f1a Atp5f1a Acss2 Acss2 I79_008051 I79_008051 Micos13 Micos13 Polg2 Polg2 Atp5me Atp5me Atp5f1d Atp5f1d Ssbp1 Ssbp1 Chchd3 Chchd3 I79_010086 I79_010086 I79_010854 I79_010854 Atp5mc1 Atp5mc1 I79_011389 I79_011389 H671_2g6475 H671_2g6475 Gabpa Gabpa I79_012047 I79_012047 CgPICR_020172 CgPICR_020172 Atp5f1b Atp5f1b Ppargc1b Ppargc1b I79_013650 I79_013650 CgPICR_005749 CgPICR_005749 Micos10 Micos10 Srfbp1 Srfbp1 Atp5mc2 Atp5mc2 Sod2 Sod2 Ppargc1a Ppargc1a Atp5mf Atp5mf I79_018057 I79_018057 Dnajc11 Dnajc11 Atp5mg Atp5mg Idh2 Idh2 I79_023247 I79_023247 Atp5pb Atp5pb I79_023736 I79_023736 Twnk Twnk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Crtc3CREB-regulated transcription coactivator 3. (175 aa)
I79_026075Isocitrate dehydrogenase [NADP], mitochondrial. (123 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa)
ATP6ATP synthase subunit a. (226 aa)
I79_000004ATP synthase subunit gamma. (298 aa)
Chchd6MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (272 aa)
Atp5poATP synthase subunit O, mitochondrial. (221 aa)
Atp5pdATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
C7H17orf80Uncharacterized protein C17orf80-like. (326 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (255 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Tmem11Transmembrane protein 11. (176 aa)
I79_003030ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (141 aa)
Nrf1Nuclear respiratory factor 1. (515 aa)
I79_003341ATP synthase subunit epsilon, mitochondrial. (51 aa)
Gabpb1GA-binding protein subunit beta-1. (383 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (278 aa)
Mtx2Metaxin-2. (265 aa)
Atp5mc3ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (141 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
I79_004557ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (114 aa)
Gabpb2GA-binding protein subunit beta-2. (409 aa)
Crtc1CREB-regulated transcription coactivator 1. (443 aa)
I79_006001ATP synthase subunit d, mitochondrial. (136 aa)
I79_007391ATP synthase subunit alpha, mitochondrial. (65 aa)
Atp5f1aATP synthase subunit alpha, mitochondrial. (285 aa)
Acss2Acetyl-coenzyme A synthetase, cytoplasmic. (391 aa)
I79_008051CREB-regulated transcription coactivator 2. (576 aa)
Micos13MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (119 aa)
Polg2DNA polymerase subunit gamma-2, mitochondrial. (51 aa)
Atp5meATP synthase subunit e, mitochondrial. (69 aa)
Atp5f1dATP synthase subunit delta, mitochondrial. (167 aa)
Ssbp1Single-stranded DNA-binding protein, mitochondrial. (148 aa)
Chchd3MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (227 aa)
I79_010086ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (107 aa)
I79_010854MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (716 aa)
Atp5mc1ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (136 aa)
I79_011389ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
H671_2g6475ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (136 aa)
GabpaGA-binding protein alpha chain. (651 aa)
I79_012047Single-stranded DNA-binding protein, mitochondrial. (83 aa)
CgPICR_020172ATP synthase subunit gamma, mitochondrial. (126 aa)
Atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (534 aa)
Ppargc1bPeroxisome proliferator-activated receptor gamma coactivator 1-beta. (843 aa)
I79_013650Peroxisome proliferator-activated receptor gamma coactivator 1-beta. (111 aa)
CgPICR_005749ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (108 aa)
Micos10MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (76 aa)
Srfbp1Serum response factor-binding protein 1. (323 aa)
Atp5mc2ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (128 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Atp5mfATP synthase subunit f, mitochondrial. (171 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Dnajc11DnaJ-like subfamily C member 11. (521 aa)
Atp5mgATP synthase subunit g, mitochondrial. (53 aa)
Idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
I79_023247CREB-regulated transcription coactivator 3. (113 aa)
Atp5pbATP synthase subunit b, mitochondrial. (235 aa)
I79_023736ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (182 aa)
TwnkTwinkle protein, mitochondrial. (690 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.