STRINGSTRING
I79_022484 I79_022484 Rap1a Rap1a Mapk3 Mapk3 I79_016797 I79_016797 Frs2 Frs2 Crk Crk Map2k2 Map2k2 Kidins220 Kidins220 Ywhab Ywhab Ngf Ngf I79_009740 I79_009740 I79_009585 I79_009585 Crkl Crkl I79_009500 I79_009500 Map2k1 Map2k1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_022484Rap guanine nucleotide exchange factor 1. (934 aa)
Rap1aRas-related protein Rap-1A. (184 aa)
Mapk3Mitogen-activated protein kinase. (408 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
CrkProto-oncogene C-crk. (327 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (380 aa)
Kidins220Kinase D-interacting substrate of 220 kDa. (1747 aa)
Ywhab14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
I79_009740B-Raf proto-oncogene serine/threonine-protein kinase. (229 aa)
I79_009585Tyrosine-protein kinase receptor. (727 aa)
CrklCrk-like protein. (303 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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