STRINGSTRING
Pcna Pcna Rpa2 Rpa2 Wrn Wrn I79_006356 I79_006356 I79_007343 I79_007343 Dna2 Dna2 Tinf2 Tinf2 I79_008624 I79_008624 Pot1 Pot1 Rpa3 Rpa3 Pold2 Pold2 I79_015395 I79_015395 Acd Acd I79_016684 I79_016684 Pold4 Pold4 Terf2ip Terf2ip Pold1 Pold1 Pold3 Pold3 I79_020554 I79_020554 FEN1 FEN1 Blm Blm I79_023244 I79_023244 Rpa1 Rpa1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Rpa2Replication protein A 32 kDa subunit. (248 aa)
WrnWerner syndrome ATP-dependent helicase-like. (1405 aa)
I79_006356DNA ligase 1; Belongs to the ATP-dependent DNA ligase family. (636 aa)
I79_007343DNA2-like helicase. (134 aa)
Dna2DNA2-like helicase. (767 aa)
Tinf2TERF1-interacting nuclear factor 2. (413 aa)
I79_008624Protection of telomeres protein 1. (265 aa)
Pot1Protection of telomeres protein 1. (375 aa)
Rpa3Replication protein A subunit-like protein. (121 aa)
Pold2DNA polymerase delta subunit 2. (487 aa)
I79_015395Replication protein A 30 kDa subunit. (333 aa)
AcdPutative adrenocortical dysplasia protein like protein. (415 aa)
I79_016684Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (421 aa)
Pold4DNA polymerase delta subunit 4. (107 aa)
Terf2ipTelomeric repeat-binding factor 2-interacting protein 1. (393 aa)
Pold1DNA polymerase. (1056 aa)
Pold3DNA polymerase delta subunit 3. (462 aa)
I79_020554Protection of telomeres protein 1. (490 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (412 aa)
BlmATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (464 aa)
I79_023244Bloom syndrome protein-like. (721 aa)
Rpa1Replication protein A 70 kDa DNA-binding subunit. (209 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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