STRINGSTRING
I79_023721 I79_023721 CgPICR_020372 CgPICR_020372 I79_025218 I79_025218 I79_025453 I79_025453 I79_025505 I79_025505 I79_025571 I79_025571 Ubc Ubc Plcg1 Plcg1 I79_014706 I79_014706 Spry1 Spry1 Fndc3a Fndc3a Nras Nras I79_012489 I79_012489 Eras Eras Sh3gl2 Sh3gl2 Csde1 Csde1 I79_010806 I79_010806 Cdc42 Cdc42 Stam Stam Spry2 Spry2 I79_008941 I79_008941 Ptprt Ptprt Sh3gl1 Sh3gl1 Shc1 Shc1 I79_007033 I79_007033 Fndc3b Fndc3b H671_xg20512 H671_xg20512 Pik3r1 Pik3r1 Eps15l1 Eps15l1 Kras Kras I79_004244 I79_004244 I79_003162 I79_003162 H671_4g12632 H671_4g12632 Rnf222 Rnf222 Src Src Hgs Hgs Eps15 Eps15 I79_001232 I79_001232 Pxn Pxn CgPICR_012052 CgPICR_012052 I79_025579 I79_025579 I79_025972 I79_025972 CgPICR_023615 CgPICR_023615 Pik3ca Pik3ca I79_017306 I79_017306 Arhgef7 Arhgef7 Sh3gl3 Sh3gl3 Hras Hras Stam2 Stam2 I79_019028 I79_019028 Tgfa Tgfa I79_020221 I79_020221 I79_020548 I79_020548 I79_021125 I79_021125 Ereg Ereg Areg Areg I79_021564 I79_021564 Aamp Aamp I79_022455 I79_022455 Csk Csk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_023721Leupaxin. (365 aa)
CgPICR_020372GTPase ERas. (182 aa)
I79_025218GTPase ERas. (178 aa)
I79_025453GTPase ERas. (177 aa)
I79_025505GTPase ERas. (96 aa)
I79_025571GTPase ERas. (155 aa)
UbcUbiquitin. (430 aa)
Plcg1Phosphoinositide phospholipase C. (1217 aa)
I79_014706GTPase ERas. (126 aa)
Spry1Protein sprouty-like 1. (313 aa)
Fndc3aFibronectin type-III domain-containing protein 3a. (1133 aa)
NrasCold shock domain-containing protein E1. (451 aa)
I79_012489Fibronectin type III domain containing 3c. (548 aa)
ErasGTPase ERas. (228 aa)
Sh3gl2Endophilin-A1. (152 aa)
Csde1Cold shock domain-containing protein E1. (95 aa)
I79_010806Cold shock domain-containing protein E1. (255 aa)
Cdc42Cell division control protein 42-like. (191 aa)
StamSignal transducing adapter molecule 1. (132 aa)
Spry2Protein sprouty-like 2. (316 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
PtprtReceptor-type tyrosine-protein phosphatase T. (320 aa)
Sh3gl1Endophilin-A2. (368 aa)
Shc1SHC-transforming protein 1. (579 aa)
I79_007033Tyrosine-protein phosphatase non-receptor type 3. (798 aa)
Fndc3bFibronectin type III domain-containing protein 3B. (1203 aa)
H671_xg20512SH3 domain-containing kinase-binding protein 1. (602 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Eps15l1Epidermal growth factor receptor substrate 15-like 1. (755 aa)
KrasGTPase KRas. (155 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
I79_003162GTPase ERas. (106 aa)
H671_4g12632GTPase ERas-like protein. (144 aa)
Rnf222RING finger protein 222. (212 aa)
SrcTyrosine-protein kinase. (536 aa)
HgsHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (776 aa)
Eps15Epidermal growth factor receptor substrate 15. (74 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
PxnPaxillin. (388 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
I79_025579GTPase ERas. (260 aa)
I79_025972Hepatocyte growth factor-regulated tyrosine kinase substrate. (147 aa)
CgPICR_023615GTPase ERas. (137 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
I79_017306GTPase ERas. (167 aa)
Arhgef7Rho guanine nucleotide exchange factor 7. (646 aa)
Sh3gl3Endophilin-A3. (274 aa)
HrasGTPase HRas-like protein. (189 aa)
Stam2Signal transducing adapter molecule 2. (523 aa)
I79_019028Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (437 aa)
TgfaProtransforming growth factor alpha. (211 aa)
I79_020221GTPase ERas. (151 aa)
I79_020548Receptor-type tyrosine-protein phosphatase kappa. (858 aa)
I79_021125Epigen. (135 aa)
EregProepiregulin. (162 aa)
AregAmphiregulin. (230 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
AampAngio-associated migratory cell protein. (389 aa)
I79_022455Receptor-type tyrosine-protein phosphatase kappa. (375 aa)
CskTyrosine-protein kinase. (450 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.