STRINGSTRING
I79_018615 I79_018615 I79_000137 I79_000137 Pdx1 Pdx1 Pax4 Pax4 Pax6 Pax6 Neurog1 Neurog1 Akt1 Akt1 Ptf1a Ptf1a I79_005543 I79_005543 I79_005719 I79_005719 Neurog3 Neurog3 Maml2 Maml2 Neurod1 Neurod1 I79_009248 I79_009248 I79_010330 I79_010330 Akt2 Akt2 I79_012461 I79_012461 I79_015503 I79_015503 Foxa2 Foxa2 Akt3 Akt3 Foxo1 Foxo1 Neurod4 Neurod4 I79_018913 I79_018913 Hnf1b Hnf1b I79_024779 I79_024779
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_018615DNA-binding protein RFX6. (582 aa)
I79_000137One cut domain family member. (431 aa)
Pdx1Pancreas/duodenum homeobox protein 1. (283 aa)
Pax4Paired box protein Pax-4. (231 aa)
Pax6Paired box protein Pax-6. (544 aa)
Neurog1Neurogenin-1. (241 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Ptf1aPancreas transcription factor 1 subunit alpha. (152 aa)
I79_005543One cut domain family member 2. (50 aa)
I79_005719Neurogenic differentiation factor 2. (352 aa)
Neurog3Neurogenin-3. (214 aa)
Maml2Mastermind-like protein 2. (914 aa)
Neurod1Neurogenic differentiation factor. (355 aa)
I79_009248One cut domain family member 3. (170 aa)
I79_010330Hepatocyte nuclear factor 1-alpha. (668 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
I79_012461Transcription factor RFX4. (659 aa)
I79_015503Transcription factor HES-1. (92 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Foxo1Forkhead box protein O1. (469 aa)
Neurod4Neurogenic differentiation factor. (331 aa)
I79_018913Homeobox protein Nkx-6.2. (114 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
I79_024779Homeobox protein Nkx-6.1. (99 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.