(28 nodes) A tetrasaccharide linker sequence is required for GAG synthesis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Xylt1	Uncharacterized protein. (136 aa)
	I79_022037	Xylosyltransferase 1. (332 aa)
	I79_020752	Chondroitin sulfate proteoglycan 4. (1364 aa)
	Sdc2	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (172 aa)
	I79_018705	Glypican-2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (444 aa)
	Agrn	Agrin. (2036 aa)
	B3galt6	Hexosyltransferase. (325 aa)
	B3gat3	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (129 aa)
	B3gat1	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (509 aa)
	I79_014935	Chondroitin sulfate proteoglycan 4. (849 aa)
	Bgn	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
	Sdc4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
	Vcan	Uncharacterized protein. (607 aa)
	Dcn	Decorin; May affect the rate of fibrils formation. (362 aa)
	Hspg2	Basement membrane-specific heparan sulfate proteoglycan core protein. (3140 aa)
	I79_009708	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
	Gpc4	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (486 aa)
	Bcan	Brevican core protein. (910 aa)
	Sdc1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (285 aa)
	Xylt2	Xylosyltransferase 2. (191 aa)
	Gpc1	Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (781 aa)
	Ncan	Neurocan core protein. (1234 aa)
	Sdc3	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (432 aa)
	H671_3g8823	Beta-1,4-galactosyltransferase 7-like protein. (327 aa)
	Cspg4	Chondroitin sulfate proteoglycan 4. (2323 aa)
	I79_001074	Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (160 aa)
	I79_000407	Glypican-6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (159 aa)
	Gpc6	Glypican-6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (244 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Agrn	Bcan	G3I437	G3HG76	Agrin.	Brevican core protein.	0.658
Agrn	Bgn	G3I437	G3HSX8	Agrin.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.712
Agrn	Dcn	G3I437	G3HJG6	Agrin.	Decorin; May affect the rate of fibrils formation.	0.707
Agrn	Gpc1	G3I437	G3H4T5	Agrin.	Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.560
Agrn	Hspg2	G3I437	G3HIM1	Agrin.	Basement membrane-specific heparan sulfate proteoglycan core protein.	0.700
Agrn	I79_009708	G3I437	G3HGH9	Agrin.	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.432
Agrn	Sdc1	G3I437	G3HDJ3	Agrin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.626
Agrn	Sdc3	G3I437	G3H1X2	Agrin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.475
Agrn	Vcan	G3I437	G3HKI0	Agrin.	Uncharacterized protein.	0.488
B3galt6	B3gat3	G3I413	G3I065	Hexosyltransferase.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.985
B3galt6	Dcn	G3I413	G3HJG6	Hexosyltransferase.	Decorin; May affect the rate of fibrils formation.	0.489
B3galt6	H671_3g8823	G3I413	G3H161	Hexosyltransferase.	Beta-1,4-galactosyltransferase 7-like protein.	0.678
B3galt6	I79_009708	G3I413	G3HGH9	Hexosyltransferase.	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.429
B3galt6	I79_022037	G3I413	G3IE93	Hexosyltransferase.	Xylosyltransferase 1.	0.409
B3galt6	Sdc1	G3I413	G3HDJ3	Hexosyltransferase.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.456
B3galt6	Xylt1	G3I413	G3IM37	Hexosyltransferase.	Uncharacterized protein.	0.409
B3galt6	Xylt2	G3I413	G3HBF2	Hexosyltransferase.	Xylosyltransferase 2.	0.778
B3gat1	B3gat3	G3HW23	G3I065	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.576
B3gat1	Bcan	G3HW23	G3HG76	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	Brevican core protein.	0.550
B3gat1	Dcn	G3HW23	G3HJG6	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	Decorin; May affect the rate of fibrils formation.	0.470