STRINGSTRING
Ubc Ubc I79_016638 I79_016638 Itgb1 Itgb1 Smad4 Smad4 Bambi Bambi Itgav Itgav Itgb3 Itgb3 Tgfb3 Tgfb3 I79_009236 I79_009236 I79_009100 I79_009100 Nedd8 Nedd8 I79_000092 I79_000092 Itgb5 Itgb5 Tgfbr2 Tgfbr2 Zfyve9 Zfyve9 I79_005093 I79_005093 Fkbp1a Fkbp1a Tgfbr1 Tgfbr1 Itgb6 Itgb6 Smad3 Smad3 Strap Strap Smad2 Smad2 Pmepa1 Pmepa1 Stub1 Stub1 I79_008298 I79_008298 I79_013902 I79_013902 I79_013556 I79_013556 Smad7 Smad7 Mtmr4 Mtmr4 I79_023010 I79_023010 fur fur Tgfb1 Tgfb1 I79_020073 I79_020073 I79_020072 I79_020072 I79_019127 I79_019127 Mzf1 Mzf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UbcUbiquitin. (430 aa)
I79_016638Protein phosphatase 1 regulatory subunit 15A. (445 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
BambiBMP and activin membrane-bound inhibitor-like. (218 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (944 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
I79_009236Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (521 aa)
I79_009100Latent-transforming growth factor beta-binding protein 1. (1194 aa)
Nedd8NEDD8. (81 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Itgb5Integrin beta; Belongs to the integrin beta chain family. (771 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Zfyve9Zinc finger FYVE domain-containing protein. (1413 aa)
I79_005093UPF0459 protein C19orf50-like. (207 aa)
Fkbp1aPeptidylprolyl isomerase. (79 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (792 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
StrapSerine-threonine kinase receptor-associated protein. (309 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Pmepa1Transmembrane prostate androgen-induced protein. (222 aa)
Stub1STIP1-likey and U box-containing protein 1. (231 aa)
I79_008298E3 ubiquitin-protein ligase SMURF2. (571 aa)
I79_013902Uncharacterized protein C18orf1-like. (259 aa)
I79_013556Fibrillin-1. (2698 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
Mtmr4Myotubularin-related protein 4. (1200 aa)
I79_023010Latent-transforming growth factor beta-binding protein 3. (624 aa)
furFurin endoprotease; Belongs to the peptidase S8 family. (794 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020073Latent-transforming growth factor beta-binding protein 2. (286 aa)
I79_020072Latent-transforming growth factor beta-binding protein 2. (52 aa)
I79_019127Integrin beta; Belongs to the integrin beta chain family. (435 aa)
Mzf1NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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