STRINGSTRING
SARS1 SARS1 I79_013548 I79_013548 Mars1 Mars1 H671_2g5865 H671_2g5865 Scly Scly I79_000086 I79_000086 I79_000303 I79_000303 I79_013121 I79_013121 I79_026058 I79_026058 I79_024746 I79_024746 Sephs2 Sephs2 Qars1 Qars1 Sepsecs Sepsecs I79_019169 I79_019169 Kars1 Kars1 Aimp2 Aimp2 Sephs1 Sephs1 Rars1 Rars1 Dars1 Dars1 Eef1e1 Eef1e1 Lars1 Lars1 I79_010044 I79_010044 Secisbp2 Secisbp2 I79_010386 I79_010386 Iars1 Iars1 Mat1a Mat1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SARS1Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16 [...] (512 aa)
I79_013548SECIS-binding protein 2-like. (1291 aa)
Mars1Methionyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (908 aa)
H671_2g5865Histamine N-methyltransferase-like protein. (320 aa)
SclySelenocysteine lyase. (392 aa)
I79_000086Bifunctional aminoacyl-tRNA synthetase. (1378 aa)
I79_000303Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (385 aa)
I79_013121Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (565 aa)
I79_026058Selenocysteine lyase. (90 aa)
I79_024746Aspartyl-tRNA synthetase, cytoplasmic. (419 aa)
Sephs2Selenide, water dikinase 2. (338 aa)
Qars1Glutaminyl-tRNA synthetase-like protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
SepsecsO-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (413 aa)
I79_01916940S ribosomal protein S17. (110 aa)
Kars1Lysine--tRNA ligase. (626 aa)
Aimp2Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2. (320 aa)
Sephs1Selenide, water dikinase 1. (392 aa)
Rars1Arginyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (542 aa)
Dars1Aspartyl-tRNA synthetase, cytoplasmic. (479 aa)
Eef1e1Eukaryotic translation elongation factor 1 epsilon-1. (98 aa)
Lars1Leucyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (727 aa)
I79_010044Leucyl-tRNA synthetase, cytoplasmic. (438 aa)
Secisbp2Selenocysteine insertion sequence-binding protein 2. (855 aa)
I79_010386Selenocysteine-specific elongation factor. (583 aa)
Iars1Isoleucyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1262 aa)
Mat1aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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