39 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gsr	Glutathione reductase, mitochondrial. (410 aa)
	Prdx3	Thioredoxin-dependent peroxide reductase, mitochondrial. (257 aa)
	Gpx1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	Pdia2	Protein disulfide-isomerase A2. (518 aa)
	I79_008148	Glutathione peroxidase 2. (151 aa)
	Prdx2	Peroxiredoxin-2. (198 aa)
	Txnrd2	Thioredoxin reductase 2, mitochondrial. (276 aa)
	I79_009034	Thioredoxin reductase 2, mitochondrial. (116 aa)
	I79_009122	Thioredoxin domain-containing protein 6. (237 aa)
	I79_009536	Neutrophil cytosol factor 2. (515 aa)
	Ncf1	Neutrophil cytosol factor 1. (303 aa)
	Gpx6	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
	Gpx5	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (192 aa)
	I79_013121	Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (565 aa)
	Sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
	I79_016007	Cytochrome b-245 heavy chain. (396 aa)
	I79_016330	Thioredoxin domain-containing protein 2. (553 aa)
	I79_018057	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	Gstp1	Glutathione S-transferase P. (221 aa)
	I79_018158	Glutathione S-transferase P 2. (210 aa)
	Ccs	Copper chaperone for superoxide dismutase. (274 aa)
	Nudt2	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Belongs to the Nudix hydrolase family. (147 aa)
	Sod3	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (245 aa)
	I79_022036	Peroxiredoxin-2. (108 aa)
	Ncf4	Neutrophil cytosol factor 4. (377 aa)
	Txn2	Thioredoxin, mitochondrial. (64 aa)
	Prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (213 aa)
	Nox4	NADPH oxidase 4. (130 aa)
	Gpx8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	P4hb	Protein disulfide-isomerase; Belongs to the protein disulfide isomerase family. (184 aa)
	Prdx1	Peroxiredoxin-1. (199 aa)
	Cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
	Gpx3	Glutathione peroxidase 3. (53 aa)
	I79_004417	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	I79_005447	Glutathione peroxidase 3. (50 aa)
	I79_000233	Cytochrome b-245 light chain. (206 aa)
	I79_000303	Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (385 aa)
	I79_001600	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
	Gpx7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cat	Gpx1	G3GYY6	G3H8G0	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.469
Cat	Gpx3	G3GYY6	G3H573	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase 3.	0.469
Cat	Gpx5	G3GYY6	G3HPX8	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.469
Cat	Gpx6	G3GYY6	G3HPX7	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.469
Cat	Gpx7	G3GYY6	G3GW03	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.591
Cat	Gpx8	G3GYY6	G3IAX4	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.591
Cat	Gsr	G3GYY6	G3H609	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione reductase, mitochondrial.	0.738
Cat	I79_000303	G3GYY6	G3GRZ6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.402
Cat	I79_005447	G3GYY6	G3H572	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase 3.	0.469
Cat	I79_008148	G3GYY6	G3HCD9	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase 2.	0.469
Cat	I79_009034	G3GYY6	G3HEP6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin reductase 2, mitochondrial.	0.402
Cat	I79_009122	G3GYY6	G3HEX5	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin domain-containing protein 6.	0.558
Cat	I79_013121	G3GYY6	G3HQL6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.402
Cat	I79_016330	G3GYY6	G3HZ35	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin domain-containing protein 2.	0.661
Cat	I79_022036	G3GYY6	G3IE92	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin-2.	0.736
Cat	Prdx1	G3GYY6	G3GYP9	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin-1.	0.736
Cat	Prdx2	G3GYY6	G3HCW9	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin-2.	0.736
Cat	Prdx3	G3GYY6	G3H7R4	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin-dependent peroxide reductase, mitochondrial.	0.736
Cat	Prdx5	G3GYY6	G3I887	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.684
Cat	Sod2	G3GYY6	G3HWB8	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.977