(31 nodes) HSF1 activation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Metrn	Meteorin. (383 aa)
	I79_008088	Heat shock protein HSP 90-beta. (412 aa)
	Eef1a2	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
	I79_026021	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (70 aa)
	I79_024259	Heat shock protein HSP 90-beta. (73 aa)
	I79_024082	Heat shock protein HSP 90-beta. (166 aa)
	Eef1a1	Elongation factor 1-alpha 1. (262 aa)
	I79_022117	Uncharacterized protein. (151 aa)
	I79_022115	Uncharacterized protein. (170 aa)
	I79_021590	Heat shock protein HSP 90-beta. (121 aa)
	I79_021309	Elongation factor 1-alpha 1. (53 aa)
	I79_021139	Heat shock protein HSP 90-beta. (113 aa)
	I79_021138	Heat shock protein HSP 90-beta. (90 aa)
	I79_018653	Heat shock protein HSP 90-beta. (131 aa)
	Nol3	Heat shock factor protein 4; Belongs to the HSF family. (915 aa)
	I79_016293	Heat shock protein HSP 90-alpha 1. (135 aa)
	I79_016292	Heat shock protein HSP 90-alpha. (205 aa)
	I79_015487	Elongation factor 1-alpha 1. (458 aa)
	I79_015356	Heat shock factor protein 1. (524 aa)
	I79_013640	Heat shock protein HSP 90-alpha. (249 aa)
	Ptges3	Prostaglandin E synthase 3. (214 aa)
	Hdac6	Histone deacetylase 6. (666 aa)
	I79_012144	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (2171 aa)
	Ptges3l	CS domain-containing protein. (137 aa)
	I79_011236	Heat shock factor protein 2. (398 aa)
	I79_010534	Elongation factor 1-alpha 1. (124 aa)
	I79_009935	Elongation factor 1-alpha 1. (503 aa)
	I79_000806	Heat shock cognate protein HSP 90-beta. (102 aa)
	CgPICR_000782	Elongation factor 1-alpha 1. (144 aa)
	Hsp90aa1	Heat shock protein HSP 90-alpha. (332 aa)
	I79_007634	Heat shock protein HSP 90-beta. (176 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CgPICR_000782	Hsp90aa1	G3GZK1	G3H354	Elongation factor 1-alpha 1.	Heat shock protein HSP 90-alpha.	0.418
CgPICR_000782	I79_011236	G3GZK1	G3HKK7	Elongation factor 1-alpha 1.	Heat shock factor protein 2.	0.426
CgPICR_000782	I79_013640	G3GZK1	G3HS15	Elongation factor 1-alpha 1.	Heat shock protein HSP 90-alpha.	0.463
CgPICR_000782	I79_015356	G3GZK1	G3HWM4	Elongation factor 1-alpha 1.	Heat shock factor protein 1.	0.451
CgPICR_000782	I79_016292	G3GZK1	G3HYZ7	Elongation factor 1-alpha 1.	Heat shock protein HSP 90-alpha.	0.463
CgPICR_000782	Nol3	G3GZK1	G3HZK7	Elongation factor 1-alpha 1.	Heat shock factor protein 4; Belongs to the HSF family.	0.426
Eef1a1	Eef1a2	G3IHP6	G3HGY8	Elongation factor 1-alpha 1.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.900
Eef1a1	I79_010534	G3IHP6	G3HIQ8	Elongation factor 1-alpha 1.	Elongation factor 1-alpha 1.	0.461
Eef1a1	I79_011236	G3IHP6	G3HKK7	Elongation factor 1-alpha 1.	Heat shock factor protein 2.	0.426
Eef1a1	I79_013640	G3IHP6	G3HS15	Elongation factor 1-alpha 1.	Heat shock protein HSP 90-alpha.	0.438
Eef1a1	I79_015356	G3IHP6	G3HWM4	Elongation factor 1-alpha 1.	Heat shock factor protein 1.	0.451
Eef1a1	I79_015487	G3IHP6	G3HWX4	Elongation factor 1-alpha 1.	Elongation factor 1-alpha 1.	0.900
Eef1a1	I79_016292	G3IHP6	G3HYZ7	Elongation factor 1-alpha 1.	Heat shock protein HSP 90-alpha.	0.438
Eef1a1	Nol3	G3IHP6	G3HZK7	Elongation factor 1-alpha 1.	Heat shock factor protein 4; Belongs to the HSF family.	0.426
Eef1a2	Eef1a1	G3HGY8	G3IHP6	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Elongation factor 1-alpha 1.	0.900
Eef1a2	I79_011236	G3HGY8	G3HKK7	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock factor protein 2.	0.426
Eef1a2	I79_015356	G3HGY8	G3HWM4	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock factor protein 1.	0.451
Eef1a2	I79_015487	G3HGY8	G3HWX4	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Elongation factor 1-alpha 1.	0.900
Eef1a2	Nol3	G3HGY8	G3HZK7	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock factor protein 4; Belongs to the HSF family.	0.426
Hdac6	Hsp90aa1	G3HND2	G3H354	Histone deacetylase 6.	Heat shock protein HSP 90-alpha.	0.497