STRINGSTRING
I79_009116 I79_009116 Nck1 Nck1 Shc2 Shc2 I79_009536 I79_009536 Itgb3 Itgb3 I79_009837 I79_009837 Itgav Itgav Cdc42 Cdc42 I79_010806 I79_010806 Csde1 Csde1 Ncf1 Ncf1 Jup Jup I79_011899 I79_011899 Prkacb Prkacb Fyn Fyn Eras Eras I79_012336 I79_012336 Akt2 Akt2 I79_012489 I79_012489 I79_012742 I79_012742 I79_012764 I79_012764 Nras Nras Fndc3a Fndc3a Elmo1 Elmo1 I79_013420 I79_013420 Ctnnd1 Ctnnd1 I79_013551 I79_013551 Nedd9 Nedd9 I79_014053 I79_014053 I79_014098 I79_014098 CgPICR_017756 CgPICR_017756 Crk Crk Sphk1 Sphk1 I79_014706 I79_014706 I79_014743 I79_014743 CgPICR_008120 CgPICR_008120 Plcg1 Plcg1 I79_015685 I79_015685 Akt3 Akt3 I79_016007 I79_016007 Pak3 Pak3 Elmo3 Elmo3 Mapk13 Mapk13 Mapk14 Mapk14 Pik3ca Pik3ca I79_017273 I79_017273 I79_017306 I79_017306 I79_017397 I79_017397 I79_017398 I79_017398 I79_017572 I79_017572 Kctd5 Kctd5 Mapk12 Mapk12 I79_017749 I79_017749 Hras Hras I79_018344 I79_018344 Bcar1 Bcar1 I79_018801 I79_018801 Actl9 Actl9 I79_018847 I79_018847 I79_019038 I79_019038 I79_019066 I79_019066 Ptk2 Ptk2 Mapkap1 Mapkap1 Wasf2 Wasf2 Trib3 Trib3 Prkcb Prkcb Stpg4 Stpg4 I79_020221 I79_020221 I79_020316 I79_020316 Hnrnpul1 Hnrnpul1 I79_020786 I79_020786 Stx7 Stx7 I79_021550 I79_021550 I79_022034 I79_022034 Mtor Mtor I79_022257 I79_022257 I79_022271 I79_022271 I79_022935 I79_022935 Prr5 Prr5 I79_023721 I79_023721 Ncf4 Ncf4 I79_023998 I79_023998 I79_024289 I79_024289 Vav2 Vav2 I79_024372 I79_024372 CgPICR_020372 CgPICR_020372 I79_024629 I79_024629 Pak1 Pak1 I79_024941 I79_024941 I79_025218 I79_025218 I79_025453 I79_025453 I79_025505 I79_025505 I79_025571 I79_025571 I79_025579 I79_025579 CgPICR_023615 CgPICR_023615 I79_009115 I79_009115 Arvcf Arvcf Prkaca Prkaca Prkca Prkca I79_008231 I79_008231 Shd Shd I79_008095 I79_008095 Mlst8 Mlst8 Calm2 Calm2 I79_007693 I79_007693 I79_007624 I79_007624 Mapkapk2 Mapkapk2 I79_007264 I79_007264 Cav1 Cav1 Actl7a Actl7a Ctnnb1 Ctnnb1 Elmo2 Elmo2 I79_006673 I79_006673 Rhoa Rhoa I79_006637 I79_006637 I79_006611 I79_006611 Mapkapk3 Mapkapk3 Shb Shb Fndc3b Fndc3b Cdh5 Cdh5 Nck2 Nck2 Pik3r1 Pik3r1 Hsh2d Hsh2d I79_005111 I79_005111 Kras Kras Akt1 Akt1 Stx12 Stx12 I79_003162 I79_003162 I79_003013 I79_003013 H671_4g12632 H671_4g12632 Rnf222 Rnf222 Src Src Wasf1 Wasf1 CgPICR_011954 CgPICR_011954 Baiap2 Baiap2 I79_002350 I79_002350 I79_002119 I79_002119 Actb Actb Rac1 Rac1 Prkcd Prkcd I79_001232 I79_001232 Pxn Pxn Pak2 Pak2 I79_000233 I79_000233
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_009116Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (311 aa)
Nck1Cytoplasmic protein NCK1. (602 aa)
Shc2SHC-transforming protein 2. (570 aa)
I79_009536Neutrophil cytosol factor 2. (515 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
I79_009837Rapamycin-insensitive companion of mTOR. (1308 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (944 aa)
Cdc42Cell division control protein 42-like. (191 aa)
I79_010806Cold shock domain-containing protein E1. (255 aa)
Csde1Cold shock domain-containing protein E1. (95 aa)
Ncf1Neutrophil cytosol factor 1. (303 aa)
JupJunction plakoglobin. (1148 aa)
I79_011899SH2 domain-containing adapter protein F. (322 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
ErasGTPase ERas. (228 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
I79_012489Fibronectin type III domain containing 3c. (548 aa)
I79_012742Actin, cytoplasmic 3. (130 aa)
I79_012764Ras GTPase-activating protein 1. (826 aa)
NrasCold shock domain-containing protein E1. (451 aa)
Fndc3aFibronectin type-III domain-containing protein 3a. (1133 aa)
Elmo1Engulfment and cell motility protein 1. (727 aa)
I79_013420Embryonal Fyn-associated substrate. (589 aa)
Ctnnd1Catenin delta-1. (932 aa)
I79_013551SHC-transforming protein 4. (202 aa)
Nedd9Enhancer of filamentation 1. (830 aa)
I79_014053Abl interactor 1. (280 aa)
I79_014098Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
CgPICR_017756Calmodulin-like protein; Belongs to the calmodulin family. (98 aa)
CrkProto-oncogene C-crk. (327 aa)
Sphk1Sphingosine kinase 1. (383 aa)
I79_014706GTPase ERas. (126 aa)
I79_014743Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
CgPICR_008120Wiskott-Aldrich syndrome protein family member 1. (650 aa)
Plcg1Phosphoinositide phospholipase C. (1217 aa)
I79_015685EF-hand domain-containing protein. (101 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
I79_016007Cytochrome b-245 heavy chain. (396 aa)
Pak3Non-specific serine/threonine protein kinase. (544 aa)
Elmo3Engulfment and cell motility protein 3. (117 aa)
Mapk13Mitogen-activated protein kinase. (278 aa)
Mapk14Mitogen-activated protein kinase. (349 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
I79_017273Protein kinase C alpha type. (128 aa)
I79_017306GTPase ERas. (167 aa)
I79_017397Protein kinase C zeta type. (280 aa)
I79_017398Protein kinase C zeta type. (53 aa)
I79_017572Target of rapamycin complex 2 subunit MAPKAP1. (140 aa)
Kctd53-phosphoinositide-dependent protein kinase 1; Belongs to the peptidase S1 family. (799 aa)
Mapk12Mitogen-activated protein kinase. (380 aa)
I79_017749Mitogen-activated protein kinase 11. (413 aa)
HrasGTPase HRas-like protein. (189 aa)
I79_018344Cytoplasmic FMR1-interacting protein 2. (1033 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1. (879 aa)
I79_018801Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (635 aa)
Actl9Actin-like protein 9; Belongs to the actin family. (377 aa)
I79_018847Calmodulin; Belongs to the calmodulin family. (152 aa)
I79_019038Nck-associated protein 1-like. (1065 aa)
I79_019066Actin, cytoplasmic 2. (291 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
Mapkap1Target of rapamycin complex 2 subunit MAPKAP1. (316 aa)
Wasf2Wiskott-Aldrich syndrome protein family member 2. (360 aa)
Trib3Tribbles-like 3. (353 aa)
PrkcbNon-specific serine/threonine protein kinase. (544 aa)
Stpg4Calmodulin; Belongs to the calmodulin family. (211 aa)
I79_020221GTPase ERas. (151 aa)
I79_020316Guanine nucleotide exchange factor VAV3. (604 aa)
Hnrnpul1Heterogeneous nuclear ribonucleoprotein U-like protein 1. (1566 aa)
I79_020786Calmodulin; Belongs to the calmodulin family. (141 aa)
Stx7Syntaxin-7; Belongs to the syntaxin family. (261 aa)
I79_021550Actin-related protein T2; Belongs to the actin family. (422 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_022257Actin. (98 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
I79_022935Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (782 aa)
Prr5Protor-1. (343 aa)
I79_023721Leupaxin. (365 aa)
Ncf4Neutrophil cytosol factor 4. (377 aa)
I79_023998Guanine nucleotide exchange factor VAV2. (93 aa)
I79_024289Actin-like protein 9; Belongs to the actin family. (411 aa)
Vav2Guanine nucleotide exchange factor VAV2. (453 aa)
I79_024372Guanine nucleotide exchange factor VAV2. (233 aa)
CgPICR_020372GTPase ERas. (182 aa)
I79_024629Actin-like protein 9; Belongs to the actin family. (384 aa)
Pak1Serine/threonine-protein kinase PAK 1. (325 aa)
I79_024941Calmodulin; Belongs to the calmodulin family. (149 aa)
I79_025218GTPase ERas. (178 aa)
I79_025453GTPase ERas. (177 aa)
I79_025505GTPase ERas. (96 aa)
I79_025571GTPase ERas. (155 aa)
I79_025579GTPase ERas. (260 aa)
CgPICR_023615GTPase ERas. (137 aa)
I79_009115Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (441 aa)
ArvcfArmadillo repeat protein deleted in velo-cardio-facial syndrome-like. (730 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PrkcaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
I79_008231Proto-oncogene vav. (879 aa)
ShdSH2 domain-containing adapter protein D-like protein. (328 aa)
I79_008095Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (213 aa)
Mlst8Target of rapamycin complex subunit LST8. (326 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (161 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
I79_007624Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
Mapkapk2MAPKAPK2. (307 aa)
I79_007264Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (84 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (440 aa)
Ctnnb1Catenin beta-1. (781 aa)
Elmo2Engulfment and cell motility protein 2. (720 aa)
I79_006673Nck-associated protein 1. (951 aa)
RhoaTransforming protein RhoA. (193 aa)
I79_006637Actin-like protein 7B; Belongs to the actin family. (1218 aa)
I79_006611MAP kinase-activated protein kinase 3. (283 aa)
Mapkapk3MAP kinase-activated protein kinase 3. (244 aa)
ShbSH2 domain-containing adapter protein B. (298 aa)
Fndc3bFibronectin type III domain-containing protein 3B. (1203 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
Nck2Cytoplasmic protein. (380 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Hsh2dHematopoietic SH2 domain-containing protein. (336 aa)
I79_005111Phosphatidylinositol 3-kinase regulatory subunit beta. (653 aa)
KrasGTPase KRas. (155 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Stx12Syntaxin-12; Belongs to the syntaxin family. (274 aa)
I79_003162GTPase ERas. (106 aa)
I79_003013Abl interactor 2. (382 aa)
H671_4g12632GTPase ERas-like protein. (144 aa)
Rnf222RING finger protein 222. (212 aa)
SrcTyrosine-protein kinase. (536 aa)
Wasf1Wiskott-Aldrich syndrome protein family member 1. (559 aa)
CgPICR_011954Actin, cytoplasmic 2; Belongs to the actin family. (244 aa)
Baiap2Brain-specific angiogenesis inhibitor 1-associated protein 2. (555 aa)
I79_002350Uncharacterized protein. (89 aa)
I79_002119Wiskott-Aldrich syndrome protein family member 3. (421 aa)
ActbActin, cytoplasmic 1. (375 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (148 aa)
PrkcdNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
PxnPaxillin. (388 aa)
Pak2Non-specific serine/threonine protein kinase. (524 aa)
I79_000233Cytochrome b-245 light chain. (206 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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