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Mcm2 Mcm2 Rpa2 Rpa2 Orc1 Orc1 Mcm10 Mcm10 I79_000636 I79_000636 Mcm8 Mcm8 Cdt1 Cdt1 Dbf4 Dbf4 Cdk3 Cdk3 I79_015395 I79_015395 Orc4 Orc4 I79_016081 I79_016081 Prim2 Prim2 Prim1 Prim1 I79_013510 I79_013510 Rpa3 Rpa3 Orc3 Orc3 Pole3 Pole3 Cdc45 Cdc45 Cdc7 Cdc7 Gmnn Gmnn Pole Pole Mcm3 Mcm3 Mcm4 Mcm4 Mcm9 Mcm9 Orc6 Orc6 Mcm5 Mcm5 Pole2 Pole2 Pola2 Pola2 Rpa1 Rpa1 I79_025902 I79_025902 Orc5 Orc5 CDC6 CDC6 Orc2 Orc2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mcm2DNA helicase; Belongs to the MCM family. (905 aa)
Rpa2Replication protein A 32 kDa subunit. (248 aa)
Orc1Origin recognition complex subunit 1. (817 aa)
Mcm10Protein MCM10-like. (888 aa)
I79_000636Transmembrane 4 L6 family member 19. (226 aa)
Mcm8DNA replication licensing factor MCM8; Belongs to the MCM family. (833 aa)
Cdt1DNA replication factor Cdt1. (553 aa)
Dbf4Protein DBF4-like A. (358 aa)
Cdk3Cell division protein kinase 3; Belongs to the protein kinase superfamily. (322 aa)
I79_015395Replication protein A 30 kDa subunit. (333 aa)
Orc4Origin recognition complex subunit 4. (105 aa)
I79_016081DNA polymerase. (1016 aa)
Prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (507 aa)
Prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
I79_013510Cell division protein kinase 2. (322 aa)
Rpa3Replication protein A subunit-like protein. (121 aa)
Orc3Origin recognition complex subunit 3. (303 aa)
Pole3DNA polymerase epsilon subunit 3. (146 aa)
Cdc45CDC45-related protein. (282 aa)
Cdc7Cell division cycle 7-related protein kinase. (572 aa)
GmnnGeminin. (202 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2174 aa)
Mcm3DNA helicase; Belongs to the MCM family. (807 aa)
Mcm4DNA helicase; Belongs to the MCM family. (862 aa)
Mcm9DNA replication licensing factor MCM9; Belongs to the MCM family. (893 aa)
Orc6Origin recognition complex subunit 6. (252 aa)
Mcm5DNA helicase; Belongs to the MCM family. (734 aa)
Pole2DNA polymerase epsilon subunit 2. (320 aa)
Pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
Rpa1Replication protein A 70 kDa DNA-binding subunit. (209 aa)
I79_025902DNA replication licensing factor MCM2. (182 aa)
Orc5Origin recognition complex subunit 5. (435 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
Orc2Origin recognition complex subunit 2. (576 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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