STRINGSTRING
Polr2h Polr2h Sf3b4 Sf3b4 Snrnp200 Snrnp200 Sf3b6 Sf3b6 I79_003075 I79_003075 I79_002824 I79_002824 Polr2a Polr2a CgPICR_018104 CgPICR_018104 Ncbp2 Ncbp2 Srsf1 Srsf1 Srsf6 Srsf6 I79_008647 I79_008647 Polr2e Polr2e CgPICR_013477 CgPICR_013477 I79_024092 I79_024092 SNRPD1 SNRPD1 I79_009902 I79_009902 I79_010162 I79_010162 I79_010679 I79_010679 Sf3b1 Sf3b1 Eftud2 Eftud2 Zmat5 Zmat5 SNRPD2 SNRPD2 Snrpe Snrpe Srsf7 Srsf7 I79_014011 I79_014011 Polr2k Polr2k Pdcd7 Pdcd7 I79_015143 I79_015143 I79_015729 I79_015729 Snrpd3 Snrpd3 I79_017595 I79_017595 Snrpb Snrpb Polr2l Polr2l Polr2c Polr2c Snrnp35 Snrnp35 Polr2f Polr2f I79_025821 I79_025821 I79_025881 I79_025881 I79_025983 I79_025983 I79_026056 I79_026056 Ybx3 Ybx3 CgPICR_017319 CgPICR_017319 Ddx23 Ddx23 Polr2d Polr2d Polr2b Polr2b I79_020059 I79_020059 Zrsr2 Zrsr2 Snrnp25 Snrnp25 CgPICR_008498 CgPICR_008498 I79_021114 I79_021114 Ybx1 Ybx1 Zcrb1 Zcrb1 Prpf8 Prpf8 Snrnp48 Snrnp48 Ddx42 Ddx42 Gtf2f1 Gtf2f1 Snrpf Snrpf Sf3b3 Sf3b3 CgPICR_007098 CgPICR_007098 Gtf2f2 Gtf2f2 I79_006299 I79_006299 I79_006282 I79_006282 Sf3b5 Sf3b5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
Sf3b4Splicing factor 3B subunit 4-like protein. (424 aa)
Snrnp200U5 small nuclear ribonucleoprotein 200 kDa helicase. (1377 aa)
Sf3b6Pre-mRNA branch site protein p14. (125 aa)
I79_003075Small nuclear ribonucleoprotein G. (51 aa)
I79_002824DNA-directed RNA polymerase II subunit RPB7. (69 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (617 aa)
CgPICR_018104Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
Ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
Srsf1Splicing factor, arginine/serine-rich 1, transcript variant 1. (248 aa)
Srsf6Splicing factor, arginine/serine-rich 6. (210 aa)
I79_008647U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1. (427 aa)
Polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (218 aa)
CgPICR_013477Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
I79_024092Pre-mRNA-processing-splicing factor 8. (189 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
I79_009902Pre-mRNA-processing factor 6. (368 aa)
I79_010162Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
I79_010679DNA-directed RNA polymerases I, II, and III subunit RPABC1. (112 aa)
Sf3b1Splicing factor 3B subunit 1-like protein. (1304 aa)
Eftud2116 kDa U5 small nuclear ribonucleoprotein component. (972 aa)
Zmat5Zinc finger matrin-type protein 5. (170 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (108 aa)
SnrpeSmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
Srsf7Splicing factor, arginine/serine-rich 7. (227 aa)
I79_014011Thioredoxin-like protein 4A. (91 aa)
Polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
Pdcd7Programmed cell death protein 7. (196 aa)
I79_015143Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
I79_015729Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (82 aa)
Snrpd3Small nuclear ribonucleoprotein Sm D3. (84 aa)
I79_017595Splicing factor 3B subunit 2. (935 aa)
SnrpbSmall nuclear ribonucleoprotein-associated protein. (223 aa)
Polr2lDNA-directed RNA polymerases I, II, and III subunit RPABC5. (109 aa)
Polr2cDNA-directed RNA polymerase II subunit RPB3. (275 aa)
Snrnp35U11/U12 small nuclear ribonucleoprotein 35 kDa protein. (246 aa)
Polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2. (121 aa)
I79_025821Pre-mRNA-processing-splicing factor 8. (264 aa)
I79_025881Pre-mRNA-processing-splicing factor 8. (318 aa)
I79_025983Pre-mRNA-processing-splicing factor 8. (197 aa)
I79_026056Pre-mRNA-processing-splicing factor 8. (184 aa)
Ybx3DNA-binding protein A. (103 aa)
CgPICR_017319DNA-directed RNA polymerases I, II, and III subunit RPABC5. (77 aa)
Ddx23Putative ATP-dependent RNA helicase DDX23. (819 aa)
Polr2dDNA-directed RNA polymerase II subunit RPB4. (104 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (807 aa)
I79_020059U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1. (181 aa)
Zrsr2U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2. (138 aa)
Snrnp25U11/U12 small nuclear ribonucleoprotein 25 kDa protein. (123 aa)
CgPICR_008498Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
I79_021114Pre-mRNA-processing factor 6. (535 aa)
Ybx1Nuclease-sensitive element-binding protein 1. (127 aa)
Zcrb1Zinc finger CCHC-type and RNA-binding motif-containing protein 1. (175 aa)
Prpf8Pre-mRNA-processing-splicing factor 8. (365 aa)
Snrnp48U11/U12 small nuclear ribonucleoprotein 48 kDa protein. (93 aa)
Ddx42ATP-dependent RNA helicase DDX42. (928 aa)
Gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (508 aa)
SnrpfSmall nuclear ribonucleoprotein F. (67 aa)
Sf3b3Splicing factor 3B subunit 3. (1217 aa)
CgPICR_007098DNA-directed RNA polymerases I, II, and III subunit RPABC5. (84 aa)
Gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
I79_006299Splicing factor 3B subunit 5. (79 aa)
I79_006282Nuclear cap-binding protein subunit 1. (581 aa)
Sf3b5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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