(100 nodes) Apoptotic execution phase network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_020387	Spectrin alpha chain, brain. (215 aa)
	Sptan1	Spectrin alpha chain, brain. (2253 aa)
	I79_021102	Histone H1.0. (178 aa)
	I79_021238	High mobility group protein B2. (83 aa)
	I79_021432	High mobility group protein B2. (84 aa)
	I79_021949	Caspase-3; Belongs to the peptidase C14A family. (195 aa)
	I79_022295	Dynamin-1-like protein. (310 aa)
	H671_1g2886	High mobility group protein B1-like protein. (169 aa)
	I79_024213	High mobility group protein B1. (114 aa)
	I79_024248	Importin subunit alpha; Functions in nuclear protein import. (538 aa)
	Casp7	Caspase-7. (303 aa)
	Sh3glb2	Endophilin-B2. (125 aa)
	I79_024699	DNAation factor subunit beta. (112 aa)
	Dffb	DNAation factor subunit beta. (381 aa)
	I79_025142	Tight junction protein ZO-2. (464 aa)
	I79_025481	Tight junction protein ZO-2. (294 aa)
	I79_025719	Tight junction protein ZO-2. (190 aa)
	I79_025812	Microtubule-associated protein. (128 aa)
	Dffa	DNAation factor subunit alpha. (119 aa)
	Casp8	Caspase-8; Belongs to the peptidase C14A family. (481 aa)
	I79_000010	Protein kinase C. (566 aa)
	I79_000111	High mobility group protein B2. (110 aa)
	I79_000141	HMG box domain-containing protein. (90 aa)
	CgPICR_005092	B-cell receptor-associated protein 31. (245 aa)
	I79_000986	High mobility group protein B1. (93 aa)
	Prkcd	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
	I79_001591	High mobility group protein 1-like 10. (120 aa)
	I79_002087	High mobility group protein B1. (220 aa)
	I79_003161	HMG box domain-containing protein. (163 aa)
	I79_003300	High mobility group protein B1. (203 aa)
	I79_003511	High mobility group protein B1. (134 aa)
	I79_003938	Lamin-L(I); Belongs to the intermediate filament family. (483 aa)
	Fnta	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. (315 aa)
	I79_004743	Intermediate filament tail domain-containing protein 1. (360 aa)
	Pkp1	Plakophilin-1. (73 aa)
	H671_1g1714	High mobility group protein B1-like protein. (154 aa)
	I79_005318	Serine/threonine-protein kinase 25. (377 aa)
	Map2	Microtubule-associated protein. (1608 aa)
	Tjp1	Tight junction protein ZO-1. (762 aa)
	I79_005692	Importin subunit beta-1. (1894 aa)
	Hmgb4	High mobility group protein B4. (106 aa)
	I79_006916	HMG box domain-containing protein. (139 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	Clspn	Claspin. (1317 aa)
	I79_008464	High mobility group protein B2. (107 aa)
	Dsp	Desmoplakin. (2836 aa)
	I79_008693	Histone H1.3. (207 aa)
	I79_008702	Histone H2A type 1; Belongs to the histone H2A family. (331 aa)
	H1-6	Histone H1t. (150 aa)
	CgPICR_009866	HIST1H1D. (212 aa)
	H1-1	Histone H1.1. (213 aa)
	Scin	Adseverin. (715 aa)
	Apc	Adenomatous polyposis coli protein. (2488 aa)
	Apc2	Adenomatous polyposis coli protein 2. (2236 aa)
	Lmna	Lamin-A/C; Belongs to the intermediate filament family. (563 aa)
	I79_009698	High mobility group protein B1. (109 aa)
	I79_009989	Cytoplasmic tyrosine-protein kinase BMX. (574 aa)
	Vim	Vimentin; Belongs to the intermediate filament family. (466 aa)
	CgPICR_015259	High mobility group protein B1-like protein. (162 aa)
	Cdh1	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (744 aa)
	Hmgb2	High mobility group protein B2. (159 aa)
	Dbnl	Drebrin-like protein. (433 aa)
	I79_012174	High mobility group protein B1. (186 aa)
	H671_3g8701	Growth arrest-specific protein 2. (314 aa)
	H1-5	Histone H1.5. (222 aa)
	Capg	Macrophage-capping protein. (305 aa)
	I79_013374	Serine/threonine-protein kinase MST4. (437 aa)
	I79_013410	Apoptotic chromatin condensation inducer in the nucleus. (1230 aa)
	I79_013516	Transmembrane protein 198. (327 aa)
	Ocln	Occludin. (488 aa)
	I79_013839	Tight junction protein ZO-3; Belongs to the MAGUK family. (723 aa)
	Lmnb2	Lamin-B2; Belongs to the intermediate filament family. (602 aa)
	Bcap31	B-cell receptor-associated protein 31. (245 aa)
	I79_014559	High mobility group protein B1. (107 aa)
	CgPICR_008092	HMGB1. (83 aa)
	I79_014743	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
	I79_015018	Histone H1oo. (285 aa)
	I79_015375	Plectin-1. (720 aa)
	I79_015376	Uncharacterized protein. (2072 aa)
	Eppk1	Epiplakin. (1488 aa)
	I79_015518	High mobility group protein 1-like 10. (90 aa)
	Gsn	Gelsolin. (658 aa)
	I79_015668	Uncharacterized protein. (115 aa)
	I79_015964	HMG box domain-containing protein. (164 aa)
	I79_016879	Alpha-adducin. (735 aa)
	I79_017543	Uncharacterized protein. (98 aa)
	I79_017547	Uncharacterized protein. (108 aa)
	Lmntd2	Uncharacterized protein C11orf35-like. (407 aa)
	I79_017963	Uncharacterized protein C11orf35-like. (249 aa)
	Hp1bp3	Heterochromatin protein 1-binding protein 3. (561 aa)
	Hmgb3	High mobility group protein B3. (200 aa)
	CgPICR_015008	Histone H1.0. (194 aa)
	I79_018920	High mobility group protein 1-like 10. (126 aa)
	Tmem198	Transmembrane protein 198. (360 aa)
	I79_019152	High mobility group protein B1. (119 aa)
	I79_019161	High mobility group protein B1. (106 aa)
	Ptk2	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
	I79_019443	Putative high mobility group protein B1-like 1. (86 aa)
	Bcap29	B-cell receptor-associated protein 29. (241 aa)
	I79_019811	High mobility group protein B2. (111 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apc	Apc2	G3HF07	G3HF78	Adenomatous polyposis coli protein.	Adenomatous polyposis coli protein 2.	0.904
Apc	Ctnnb1	G3HF07	G3H996	Adenomatous polyposis coli protein.	Catenin beta-1.	0.999
Apc	I79_021949	G3HF07	G3IE08	Adenomatous polyposis coli protein.	Caspase-3; Belongs to the peptidase C14A family.	0.655
Apc2	Apc	G3HF78	G3HF07	Adenomatous polyposis coli protein 2.	Adenomatous polyposis coli protein.	0.904
Apc2	Ctnnb1	G3HF78	G3H996	Adenomatous polyposis coli protein 2.	Catenin beta-1.	0.995
Apc2	I79_021949	G3HF78	G3IE08	Adenomatous polyposis coli protein 2.	Caspase-3; Belongs to the peptidase C14A family.	0.561
Bcap29	Bcap31	G3I7S8	G3HSX3	B-cell receptor-associated protein 29.	B-cell receptor-associated protein 31.	0.489
Bcap29	Casp8	G3I7S8	B2CMK5	B-cell receptor-associated protein 29.	Caspase-8; Belongs to the peptidase C14A family.	0.679
Bcap29	CgPICR_005092	G3I7S8	G3GTA2	B-cell receptor-associated protein 29.	B-cell receptor-associated protein 31.	0.492
Bcap29	I79_022295	G3I7S8	G3IEY5	B-cell receptor-associated protein 29.	Dynamin-1-like protein.	0.553
Bcap31	Bcap29	G3HSX3	G3I7S8	B-cell receptor-associated protein 31.	B-cell receptor-associated protein 29.	0.489
Bcap31	Casp8	G3HSX3	B2CMK5	B-cell receptor-associated protein 31.	Caspase-8; Belongs to the peptidase C14A family.	0.757
Bcap31	CgPICR_005092	G3HSX3	G3GTA2	B-cell receptor-associated protein 31.	B-cell receptor-associated protein 31.	0.900
Bcap31	I79_022295	G3HSX3	G3IEY5	B-cell receptor-associated protein 31.	Dynamin-1-like protein.	0.555
Capg	Casp7	G3HPZ5	G3IL63	Macrophage-capping protein.	Caspase-7.	0.502
Capg	Casp8	G3HPZ5	B2CMK5	Macrophage-capping protein.	Caspase-8; Belongs to the peptidase C14A family.	0.447
Capg	I79_021949	G3HPZ5	G3IE08	Macrophage-capping protein.	Caspase-3; Belongs to the peptidase C14A family.	0.554
Casp7	Capg	G3IL63	G3HPZ5	Caspase-7.	Macrophage-capping protein.	0.502
Casp7	Casp8	G3IL63	B2CMK5	Caspase-7.	Caspase-8; Belongs to the peptidase C14A family.	0.968
Casp7	Cdh1	G3IL63	G3HKU8	Caspase-7.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.508