STRINGSTRING
I79_011318 I79_011318 Runx2 Runx2 Znf423 Znf423 Hey2 Hey2 I79_015503 I79_015503 I79_015033 I79_015033 Sp7 Sp7 Znf521 Znf521
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_011318Zinc finger protein 521. (472 aa)
Runx2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
Znf423Zinc finger protein 423. (1224 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
I79_015503Transcription factor HES-1. (92 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
Sp7Transcription factor Sp7. (411 aa)
Znf521Zinc finger protein 521. (857 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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