(25 nodes) (2006) Hendra and Nipah viruses: different and dangerous. network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fur	Furin endoprotease; Belongs to the peptidase S8 family. (794 aa)
	I79_026231	Ephrin-B2; Belongs to the ephrin family. (68 aa)
	Ephb2	Ephrin type-B receptor 2. (1018 aa)
	I79_025535	Ephrin-B2. (125 aa)
	Ifnar1	Interferon-alpha/beta receptor alpha chain. (483 aa)
	I79_001024	Ephrin-B2; Belongs to the ephrin family. (373 aa)
	Tyk2	Tyrosine-protein kinase. (1182 aa)
	Rnasel	2-5A-dependent ribonuclease. (525 aa)
	I79_025726	Ephrin-B2. (121 aa)
	Stat3	Signal transducer and activator of transcription. (770 aa)
	Stat2	Signal transducer and activator of transcription. (806 aa)
	I79_013907	Ephrin-B2. (148 aa)
	I79_015109	Interleukin-6. (174 aa)
	Jak1	Tyrosine-protein kinase. (1140 aa)
	I79_019922	Serine/threonine-protein kinase TBK1. (421 aa)
	Stat1	Signal transducer and activator of transcription. (749 aa)
	I79_021151	Ephrin-B2. (178 aa)
	Cd46	Membrane cofactor protein. (280 aa)
	Tlr3	Toll-like receptor 3. (164 aa)
	I79_024975	Ephrin-B2. (148 aa)
	I79_025433	Ephrin-B2; Belongs to the ephrin family. (70 aa)
	I79_025440	Cathepsin L1; Belongs to the peptidase C1 family. (333 aa)
	I79_025496	Ephrin-B2. (147 aa)
	I79_025497	Ephrin-B2; Belongs to the ephrin family. (69 aa)
	I79_025518	Ephrin-B2. (123 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ephb2	I79_001024	G3HIN4	G3GTN7	Ephrin type-B receptor 2.	Ephrin-B2; Belongs to the ephrin family.	0.948
Ephb2	I79_013907	G3HIN4	G3HSR3	Ephrin type-B receptor 2.	Ephrin-B2.	0.948
Ephb2	I79_021151	G3HIN4	G3IBW8	Ephrin type-B receptor 2.	Ephrin-B2.	0.948
Ephb2	I79_024975	G3HIN4	G3IM42	Ephrin type-B receptor 2.	Ephrin-B2.	0.948
Ephb2	I79_025433	G3HIN4	G3INB8	Ephrin type-B receptor 2.	Ephrin-B2; Belongs to the ephrin family.	0.948
Ephb2	I79_025496	G3HIN4	G3INH2	Ephrin type-B receptor 2.	Ephrin-B2.	0.948
Ephb2	I79_025497	G3HIN4	G3INH3	Ephrin type-B receptor 2.	Ephrin-B2; Belongs to the ephrin family.	0.994
Ephb2	I79_025518	G3HIN4	G3INJ3	Ephrin type-B receptor 2.	Ephrin-B2.	0.994
Ephb2	I79_025535	G3HIN4	G3INK8	Ephrin type-B receptor 2.	Ephrin-B2.	0.948
Ephb2	I79_025726	G3HIN4	G3IP25	Ephrin type-B receptor 2.	Ephrin-B2.	0.948
Ephb2	I79_026231	G3HIN4	G3IQC0	Ephrin type-B receptor 2.	Ephrin-B2; Belongs to the ephrin family.	0.994
I79_001024	Ephb2	G3GTN7	G3HIN4	Ephrin-B2; Belongs to the ephrin family.	Ephrin type-B receptor 2.	0.948
I79_013907	Ephb2	G3HSR3	G3HIN4	Ephrin-B2.	Ephrin type-B receptor 2.	0.948
I79_015109	I79_019922	G3HVW6	G3I8P6	Interleukin-6.	Serine/threonine-protein kinase TBK1.	0.429
I79_015109	Jak1	G3HVW6	G3HY52	Interleukin-6.	Tyrosine-protein kinase.	0.747
I79_015109	Stat1	G3HVW6	G3I9F9	Interleukin-6.	Signal transducer and activator of transcription.	0.794
I79_015109	Stat2	G3HVW6	G3HRN9	Interleukin-6.	Signal transducer and activator of transcription.	0.696
I79_015109	Stat3	G3HVW6	G3HLW9	Interleukin-6.	Signal transducer and activator of transcription.	0.912
I79_015109	Tlr3	G3HVW6	G3IHU2	Interleukin-6.	Toll-like receptor 3.	0.658
I79_015109	Tyk2	G3HVW6	G3H6C9	Interleukin-6.	Tyrosine-protein kinase.	0.775