(6 nodes) (2006) In vitro immune toxicity of depleted uranium: effects on murine macrophages, CD4+ T cells, and gene expression profiles. network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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textmining

co-expression

protein homology

Your Input:
	Il15	Interleukin; Belongs to the IL-15/IL-21 family. (155 aa)
	Mdk	Midkine. (160 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Cd8a	T-cell surface glycoprotein CD8 alpha chain. (144 aa)
	Il10	Interleukin-10. (178 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Cd8a	G3GUN9	G3HJJ9	T-cell surface glycoprotein CD4.	T-cell surface glycoprotein CD8 alpha chain.	0.981
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Il15	G3GUN9	G3HJ60	T-cell surface glycoprotein CD4.	Interleukin; Belongs to the IL-15/IL-21 family.	0.915
Cd4	Tnf	G3GUN9	G3HZG9	T-cell surface glycoprotein CD4.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.884
Cd8a	Cd4	G3HJJ9	G3GUN9	T-cell surface glycoprotein CD8 alpha chain.	T-cell surface glycoprotein CD4.	0.981
Cd8a	Il10	G3HJJ9	G3HB01	T-cell surface glycoprotein CD8 alpha chain.	Interleukin-10.	0.632
Cd8a	Il15	G3HJJ9	G3HJ60	T-cell surface glycoprotein CD8 alpha chain.	Interleukin; Belongs to the IL-15/IL-21 family.	0.574
Cd8a	Tnf	G3HJJ9	G3HZG9	T-cell surface glycoprotein CD8 alpha chain.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.695
Il10	Cd4	G3HB01	G3GUN9	Interleukin-10.	T-cell surface glycoprotein CD4.	0.968
Il10	Cd8a	G3HB01	G3HJJ9	Interleukin-10.	T-cell surface glycoprotein CD8 alpha chain.	0.632
Il10	Il15	G3HB01	G3HJ60	Interleukin-10.	Interleukin; Belongs to the IL-15/IL-21 family.	0.905
Il10	Tnf	G3HB01	G3HZG9	Interleukin-10.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.905
Il15	Cd4	G3HJ60	G3GUN9	Interleukin; Belongs to the IL-15/IL-21 family.	T-cell surface glycoprotein CD4.	0.915
Il15	Cd8a	G3HJ60	G3HJJ9	Interleukin; Belongs to the IL-15/IL-21 family.	T-cell surface glycoprotein CD8 alpha chain.	0.574
Il15	Il10	G3HJ60	G3HB01	Interleukin; Belongs to the IL-15/IL-21 family.	Interleukin-10.	0.905
Il15	Tnf	G3HJ60	G3HZG9	Interleukin; Belongs to the IL-15/IL-21 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.815
Tnf	Cd4	G3HZG9	G3GUN9	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	T-cell surface glycoprotein CD4.	0.884
Tnf	Cd8a	G3HZG9	G3HJJ9	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	T-cell surface glycoprotein CD8 alpha chain.	0.695
Tnf	Il10	G3HZG9	G3HB01	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Interleukin-10.	0.905
Tnf	Il15	G3HZG9	G3HJ60	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Interleukin; Belongs to the IL-15/IL-21 family.	0.815