STRINGSTRING
I79_007548 I79_007548 Aph1a Aph1a Nog Nog Dll4 Dll4 I79_021283 I79_021283 Hey2 Hey2 Epo Epo Hif1a Hif1a Smad4 Smad4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_007548Angiopoietin-1. (112 aa)
Aph1aGamma-secretase subunit APH-1A. (247 aa)
NogNoggin. (117 aa)
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
I79_021283Angiopoietin-1. (298 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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