STRINGSTRING
Nras Nras Numb Numb Fyn Fyn Stat3 Stat3 Cdc42 Cdc42 Itgb3 Itgb3 Tgfb3 Tgfb3 Rdx Rdx Flnb Flnb Hck Hck Bcl2 Bcl2 Rheb Rheb Cav1 Cav1 Cav2 Cav2 Lck Lck Itgb2 Itgb2 Itgb6 Itgb6 Rhoa Rhoa Tln2 Tln2 I79_004417 I79_004417 Isl1 Isl1 Cav3 Cav3 Flnc Flnc Vcl Vcl I79_001600 I79_001600 I79_001232 I79_001232 Pxn Pxn Esr1 Esr1 CgPICR_012052 CgPICR_012052 Itgb5 Itgb5 Jag1 Jag1 I79_000092 I79_000092 ilk ilk Casp8 Casp8 Rras Rras Ar Ar I79_022257 I79_022257 Dll4 Dll4 Hip1r Hip1r Flna Flna Rap1a Rap1a Sos2 Sos2 Fgr Fgr Fermt3 Fermt3 I79_019286 I79_019286 NOTCH1 NOTCH1 I79_019127 I79_019127 Fermt2 Fermt2 Itga5 Itga5 I79_018057 I79_018057 Lyn Lyn Itgb1 Itgb1 Msn Msn Ezr Ezr Plxnd1 Plxnd1 PPARG PPARG I79_014831 I79_014831 Smad4 Smad4 Rras2 Rras2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NrasCold shock domain-containing protein E1. (451 aa)
NumbProtein numb-like; Belongs to the histone H2A family. (702 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Cdc42Cell division control protein 42-like. (191 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
RdxRadixin. (583 aa)
FlnbFilamin-B. (2602 aa)
HckTyrosine-protein kinase. (503 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
RhebGTP-binding protein Rheb. (179 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
LckProto-oncogene tyrosine-protein kinase LCK. (158 aa)
Itgb2Integrin beta. (769 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (792 aa)
RhoaTransforming protein RhoA. (193 aa)
Tln2Talin-2. (2542 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
FlncFilamin-C. (2664 aa)
VclVinculin. (1143 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
PxnPaxillin. (388 aa)
Esr1Estrogen receptor. (200 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
Itgb5Integrin beta; Belongs to the integrin beta chain family. (771 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
RrasRas-related protein R-Ras. (126 aa)
ArAndrogen receptor. (517 aa)
I79_022257Actin. (98 aa)
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
Hip1rHuntingtin-interacting protein 1-related protein. (505 aa)
FlnaFilamin-A. (2488 aa)
Rap1aRas-related protein Rap-1A. (184 aa)
Sos2Son of sevenless-like 2. (166 aa)
FgrTyrosine-protein kinase. (435 aa)
Fermt3Fermitin family-like 3. (665 aa)
I79_019286Androgen receptor. (295 aa)
NOTCH1Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2527 aa)
I79_019127Integrin beta; Belongs to the integrin beta chain family. (435 aa)
Fermt2Fermitin family-like 2. (575 aa)
Itga5Integrin alpha-5; Belongs to the integrin alpha chain family. (729 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LynTyrosine-protein kinase. (289 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
MsnMoesin. (293 aa)
EzrEzrin. (586 aa)
Plxnd1Plexin-D1. (612 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_014831Integrin beta; Belongs to the integrin beta chain family. (721 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Rras2Ras-related protein R-Ras2. (154 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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