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Dll1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa) | ||||
NOTCH1 | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2527 aa) | ||||
B4galt1 | Beta-1,4-galactosyltransferase 1. (258 aa) | ||||
Jag1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa) |