(11 nodes) (2012) Are basophils important mediators for helminth-induced Th2 immune responses? A debate. network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	Gata3	Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Calr3	Calreticulin. (380 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5. (118 aa)
	Cd86	T-lymphocyte activation antigen CD86. (269 aa)
	Il10	Interleukin-10. (178 aa)
	Calr	Calreticulin. (417 aa)
	Stat6	Signal transducer and activator of transcription. (844 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Calr	Calr3	G3HCX8	G3H4H3	Calreticulin.	Calreticulin.	0.558
Calr	Cd4	G3HCX8	G3GUN9	Calreticulin.	T-cell surface glycoprotein CD4.	0.695
Calr	Ifng	G3HCX8	G3GY20	Calreticulin.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.455
Calr3	Calr	G3H4H3	G3HCX8	Calreticulin.	Calreticulin.	0.558
Calr3	Cd4	G3H4H3	G3GUN9	Calreticulin.	T-cell surface glycoprotein CD4.	0.656
Calr3	Ifng	G3H4H3	G3GY20	Calreticulin.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.512
Cd4	Calr	G3GUN9	G3HCX8	T-cell surface glycoprotein CD4.	Calreticulin.	0.695
Cd4	Calr3	G3GUN9	G3H4H3	T-cell surface glycoprotein CD4.	Calreticulin.	0.656
Cd4	Cd40	G3GUN9	G3H8U5	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.949
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Cd86	G3GUN9	G3HAJ6	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD86.	0.955
Cd4	Gata3	G3GUN9	G3GR59	T-cell surface glycoprotein CD4.	Trans-acting T-cell-specific transcription factor GATA-3.	0.885
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Stat6	G3GUN9	G3HW32	T-cell surface glycoprotein CD4.	Signal transducer and activator of transcription.	0.861
Cd4	Tnf	G3GUN9	G3HZG9	T-cell surface glycoprotein CD4.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.884
Cd40	Cd4	G3H8U5	G3GUN9	Tumor necrosis factor receptor superfamily member 5.	T-cell surface glycoprotein CD4.	0.949
Cd40	Cd80	G3H8U5	G3I1J7	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD80.	0.963
Cd40	Cd86	G3H8U5	G3HAJ6	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD86.	0.968
Cd40	Gata3	G3H8U5	G3GR59	Tumor necrosis factor receptor superfamily member 5.	Trans-acting T-cell-specific transcription factor GATA-3.	0.435