STRINGSTRING
Ifnar1 Ifnar1 Traf6 Traf6 Mavs Mavs Tyk2 Tyk2 Il10 Il10 Irf9 Irf9 Rnasel Rnasel Myd88 Myd88 Ifit2 Ifit2 Stat2 Stat2 Irak1 Irak1 CgPICR_014700 CgPICR_014700 Tlr4 Tlr4 Stat1 Stat1 Tlr8 Tlr8 Tlr7 Tlr7 Irak4 Irak4 Tlr3 Tlr3 CgPICR_006550 CgPICR_006550 Tlr6 Tlr6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ifnar1Interferon-alpha/beta receptor alpha chain. (483 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
MavsMitochondrial antiviral-signaling protein. (505 aa)
Tyk2Tyrosine-protein kinase. (1182 aa)
Il10Interleukin-10. (178 aa)
Irf9Interferon regulatory factor 9. (398 aa)
Rnasel2-5A-dependent ribonuclease. (525 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
Ifit2Interferon-induced protein with tetratricopeptide repeats 2. (444 aa)
Stat2Signal transducer and activator of transcription. (806 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (494 aa)
CgPICR_014700C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
Tlr8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1027 aa)
Tlr7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
Irak4Interleukin-1 receptor-associated kinase 4. (462 aa)
Tlr3Toll-like receptor 3. (164 aa)
CgPICR_006550Interferon-induced protein with tetratricopeptide repeats 1. (410 aa)
Tlr6Toll-like receptor. (795 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.