STRINGSTRING
Nos1 Nos1 Lyrm9 Lyrm9 Casp8 Casp8 Pink1 Pink1 Map1s Map1s I79_004417 I79_004417 Orai1 Orai1 Arg2 Arg2 Map1a Map1a I79_001600 I79_001600 I79_001343 I79_001343 I79_023112 I79_023112 Bnip3 Bnip3 Atp13a2 Atp13a2 I79_021949 I79_021949 HSPA5 HSPA5 I79_018057 I79_018057 Stim1 Stim1 I79_016240 I79_016240 I79_016138 I79_016138 I79_015109 I79_015109 Becn1 Becn1 Glul-2 Glul-2 Steap2 Steap2 I79_010620 I79_010620 Map1b Map1b Glul Glul Hfe Hfe Bcl2 Bcl2 I79_007693 I79_007693
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Pink1Serine/threonine-protein kinase PINK1, mitochondrial. (451 aa)
Map1sMicrotubule-associated protein 1S. (870 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Orai1Calcium release-activated calcium channel protein 1. (237 aa)
Arg2Arginase. (305 aa)
Map1aMicrotubule-associated protein 1A. (2585 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
I79_001343Alpha-2-macroglobulin. (1664 aa)
I79_023112Glutamine synthetase; Belongs to the glutamine synthetase family. (130 aa)
Bnip3BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (151 aa)
Atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (578 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] (654 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Stim1Stromal interaction molecule 1. (716 aa)
I79_016240Beclin-1. (119 aa)
I79_016138Hephaestin; Belongs to the multicopper oxidase family. (1087 aa)
I79_015109Interleukin-6. (174 aa)
Becn1Beclin-1. (448 aa)
Glul-2Glutamine synthetase. (373 aa)
Steap2Metalloreductase STEAP2. (489 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Map1bMicrotubule-associated protein 1B. (2371 aa)
GlulGlutamine synthetase; Belongs to the glutamine synthetase family. (297 aa)
HfeHereditary hemochromatosis protein-like; Belongs to the MHC class I family. (306 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: medium (48%) [HD]