(29 nodes) (2014) Methyl jasmonate: putative mechanisms of action on cancer cells cycle, metabolism, and apoptosis. network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	Gpx7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
	Casp8	Caspase-8; Belongs to the peptidase C14A family. (481 aa)
	I79_001600	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
	Vdac2	Voltage-dependent anion-selective channel protein 2. (295 aa)
	Hk3	Hexokinase-3. (867 aa)
	Vdac1	Voltage-dependent anion-selective channel protein 1. (484 aa)
	I79_004417	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	Pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	Gpx3	Glutathione peroxidase 3. (53 aa)
	Hk1	Hexokinase-1. (917 aa)
	Hkdc1	Putative hexokinase HKDC1. (925 aa)
	Gpx1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	Gsk3b	Glycogen synthase kinase-3 beta. (328 aa)
	CgPICR_016658	Voltage-dependent anion-selective channel protein 1. (129 aa)
	Bcl2	Apoptosis regulator Bcl-2. (203 aa)
	I79_009215	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (199 aa)
	Akr1b1	Aldose reductase. (316 aa)
	Gck	Phosphotransferase. (465 aa)
	Gpx6	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
	Gpx5	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (192 aa)
	I79_013395	Matrix metalloproteinase-14. (539 aa)
	Sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
	I79_018057	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	Htra2	Serine protease HTRA2, mitochondrial. (448 aa)
	I79_020089	Caspase-9; Belongs to the peptidase C14A family. (689 aa)
	Gpx8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	I79_021949	Caspase-3; Belongs to the peptidase C14A family. (195 aa)
	Hk2	Hexokinase-2. (704 aa)
	CHO-CR	Carbonyl reductase [NADPH] 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akr1b1	Gck	G3HH30	G3HMA6	Aldose reductase.	Phosphotransferase.	0.858
Akr1b1	Hk1	G3HH30	G3H6T5	Aldose reductase.	Hexokinase-1.	0.823
Akr1b1	Hk2	G3HH30	G3IGL3	Aldose reductase.	Hexokinase-2.	0.826
Akr1b1	Hk3	G3HH30	G3H184	Aldose reductase.	Hexokinase-3.	0.831
Akr1b1	Hkdc1	G3HH30	G3H6T6	Aldose reductase.	Putative hexokinase HKDC1.	0.825
Bcl2	Casp8	G3HD46	B2CMK5	Apoptosis regulator Bcl-2.	Caspase-8; Belongs to the peptidase C14A family.	0.860
Bcl2	Gpx1	G3HD46	G3H8G0	Apoptosis regulator Bcl-2.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.536
Bcl2	Gpx3	G3HD46	G3H573	Apoptosis regulator Bcl-2.	Glutathione peroxidase 3.	0.525
Bcl2	Gpx5	G3HD46	G3HPX8	Apoptosis regulator Bcl-2.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.505
Bcl2	Gpx6	G3HD46	G3HPX7	Apoptosis regulator Bcl-2.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.504
Bcl2	Gpx7	G3HD46	G3GW03	Apoptosis regulator Bcl-2.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.525
Bcl2	Gpx8	G3HD46	G3IAX4	Apoptosis regulator Bcl-2.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.526
Bcl2	Htra2	G3HD46	G3I7U9	Apoptosis regulator Bcl-2.	Serine protease HTRA2, mitochondrial.	0.405
Bcl2	I79_001600	G3HD46	G3GV69	Apoptosis regulator Bcl-2.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.993
Bcl2	I79_004417	G3HD46	G3H2K2	Apoptosis regulator Bcl-2.	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.994
Bcl2	I79_009215	G3HD46	G3HF60	Apoptosis regulator Bcl-2.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.525
Bcl2	I79_018057	G3HD46	G3I3P7	Apoptosis regulator Bcl-2.	Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.994
Bcl2	I79_020089	G3HD46	G3I954	Apoptosis regulator Bcl-2.	Caspase-9; Belongs to the peptidase C14A family.	0.970
Bcl2	I79_021949	G3HD46	G3IE08	Apoptosis regulator Bcl-2.	Caspase-3; Belongs to the peptidase C14A family.	0.938
Bcl2	Vdac2	G3HD46	G3GWR2	Apoptosis regulator Bcl-2.	Voltage-dependent anion-selective channel protein 2.	0.428