STRINGSTRING
Bcl2 Bcl2 Hmox1 Hmox1 I79_020089 I79_020089 Xiap Xiap Cxcl12 Cxcl12 Gstp1 Gstp1 I79_018057 I79_018057 Got2 Got2 Nqo1 Nqo1 Foxo1 Foxo1 Tradd Tradd I79_015109 I79_015109 Stat3 Stat3 I79_021045 I79_021045 Cck Cck Mmp9 Mmp9 Gpx1 Gpx1 Keap1 Keap1 Cdc25b Cdc25b Mcl1 Mcl1 Npy Npy I79_004417 I79_004417 Got1 Got1 Cxcr4 Cxcr4 Ifng Ifng I79_001600 I79_001600 Casp8 Casp8 Ccnd1 Ccnd1 ICAM1 ICAM1 Traf1 Traf1 Ache Ache Jak2 Jak2 I79_021949 I79_021949
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
I79_020089Caspase-9; Belongs to the peptidase C14A family. (689 aa)
XiapBaculoviral IAP repeat-containing protein 4. (441 aa)
Cxcl12Stromal cell-derived factor 1. (89 aa)
Gstp1Glutathione S-transferase P. (221 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Got2Aspartate aminotransferase. (430 aa)
Nqo1NAD(P)H dehydrogenase [quinone] 1. (274 aa)
Foxo1Forkhead box protein O1. (469 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (306 aa)
I79_015109Interleukin-6. (174 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
I79_021045Heme oxygenase 1. (81 aa)
CckCholecystokinin. (115 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
Keap1Kelch-like ECH-associated protein 1. (624 aa)
Cdc25bM-phase inducer phosphatase 2. (480 aa)
Mcl1Putative induced myeloid leukemia cell differentiation protein Mcl-1 like protein. (120 aa)
NpyNeuropeptide Y. (148 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Got1Aspartate aminotransferase. (413 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
ICAM1Intercellular adhesion molecule 1. (527 aa)
Traf1TNF receptor-associated factor 1. (298 aa)
AcheCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (575 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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