(9 nodes) (2014) Whats behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity. network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Hyal2	Hyaluronidase. (359 aa)
	Entpd1	Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (269 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	I79_025220	Serum albumin. (186 aa)
	Alb	Serum albumin. (430 aa)
	Entpd8	Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (466 aa)
	I79_008620	Hyaluronidase. (211 aa)
	Il10	Interleukin-10. (178 aa)
	Cd86	T-lymphocyte activation antigen CD86. (269 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alb	Cd4	G3IAL6	G3GUN9	Serum albumin.	T-cell surface glycoprotein CD4.	0.860
Alb	Cd86	G3IAL6	G3HAJ6	Serum albumin.	T-lymphocyte activation antigen CD86.	0.473
Alb	Hyal2	G3IAL6	G3H8C4	Serum albumin.	Hyaluronidase.	0.525
Alb	I79_008620	G3IAL6	G3HDN4	Serum albumin.	Hyaluronidase.	0.509
Alb	I79_025220	G3IAL6	G3IMS5	Serum albumin.	Serum albumin.	0.960
Alb	Il10	G3IAL6	G3HB01	Serum albumin.	Interleukin-10.	0.655
Cd4	Alb	G3GUN9	G3IAL6	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	Cd86	G3GUN9	G3HAJ6	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD86.	0.955
Cd4	Entpd1	G3GUN9	G3GZT9	T-cell surface glycoprotein CD4.	Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.	0.521
Cd4	Hyal2	G3GUN9	G3H8C4	T-cell surface glycoprotein CD4.	Hyaluronidase.	0.646
Cd4	I79_008620	G3GUN9	G3HDN4	T-cell surface glycoprotein CD4.	Hyaluronidase.	0.646
Cd4	I79_025220	G3GUN9	G3IMS5	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd86	Alb	G3HAJ6	G3IAL6	T-lymphocyte activation antigen CD86.	Serum albumin.	0.473
Cd86	Cd4	G3HAJ6	G3GUN9	T-lymphocyte activation antigen CD86.	T-cell surface glycoprotein CD4.	0.955
Cd86	I79_008620	G3HAJ6	G3HDN4	T-lymphocyte activation antigen CD86.	Hyaluronidase.	0.408
Cd86	I79_025220	G3HAJ6	G3IMS5	T-lymphocyte activation antigen CD86.	Serum albumin.	0.473
Cd86	Il10	G3HAJ6	G3HB01	T-lymphocyte activation antigen CD86.	Interleukin-10.	0.896
Entpd1	Cd4	G3GZT9	G3GUN9	Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.	T-cell surface glycoprotein CD4.	0.521
Entpd1	Entpd8	G3GZT9	G3I5Y1	Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.	Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family.	0.907