(21 nodes) (2014) TXNDC5, a newly discovered disulfide isomerase with a key role in cell physiology and pathology. network (Cricetulus griseus)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	Aldoc	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	Pdia5	Protein disulfide-isomerase A5. (504 aa)
	Apob	Apolipoprotein B-100. (3537 aa)
	Ctsb	Cathepsin B; Belongs to the peptidase C1 family. (339 aa)
	Adipor1	Adiponectin receptor protein 1. (375 aa)
	Adipor2	Adiponectin receptor protein 2. (386 aa)
	Dnajc10	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (793 aa)
	Pdia6	Protein disulfide-isomerase A6. (259 aa)
	Cdk5	Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	Prdx2	Peroxiredoxin-2. (198 aa)
	Bmp6	Bone morphogenetic protein 6. (296 aa)
	Adcy4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1022 aa)
	Adcy2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (999 aa)
	Erp44	Endoplasmic reticulum resident protein ERp44. (258 aa)
	Ins	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
	Adipoq	Adiponectin. (248 aa)
	Adcy6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	Prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (213 aa)
	Nenf	Neudesin. (70 aa)
	I79_022036	Peroxiredoxin-2. (108 aa)
	Znhit2	Zinc finger HIT domain-containing protein 2. (398 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adcy2	Adcy4	G3HQE5	G3HDI3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.415
Adcy2	Adcy6	G3HQE5	G3I6K2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.751
Adcy4	Adcy2	G3HDI3	G3HQE5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.415
Adcy4	Adcy6	G3HDI3	G3I6K2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.965
Adcy4	Ins	G3HDI3	G3HXZ8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.416
Adcy6	Adcy2	G3I6K2	G3HQE5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.751
Adcy6	Adcy4	G3I6K2	G3HDI3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.965
Adipoq	Adipor1	G3HYG0	G3H3L5	Adiponectin.	Adiponectin receptor protein 1.	0.994
Adipoq	Adipor2	G3HYG0	G3H867	Adiponectin.	Adiponectin receptor protein 2.	0.996
Adipoq	Apob	G3HYG0	G3GZQ0	Adiponectin.	Apolipoprotein B-100.	0.570
Adipoq	Ins	G3HYG0	G3HXZ8	Adiponectin.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.932
Adipor1	Adipoq	G3H3L5	G3HYG0	Adiponectin receptor protein 1.	Adiponectin.	0.994
Adipor1	Adipor2	G3H3L5	G3H867	Adiponectin receptor protein 1.	Adiponectin receptor protein 2.	0.975
Adipor1	Ins	G3H3L5	G3HXZ8	Adiponectin receptor protein 1.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.519
Adipor2	Adipoq	G3H867	G3HYG0	Adiponectin receptor protein 2.	Adiponectin.	0.996
Adipor2	Adipor1	G3H867	G3H3L5	Adiponectin receptor protein 2.	Adiponectin receptor protein 1.	0.975
Adipor2	Ins	G3H867	G3HXZ8	Adiponectin receptor protein 2.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.494
Aldoc	Nenf	G3IK44	G3I9A3	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Neudesin.	0.567
Aldoc	Znhit2	G3IK44	G3IJ17	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Zinc finger HIT domain-containing protein 2.	0.583
Apob	Adipoq	G3GZQ0	G3HYG0	Apolipoprotein B-100.	Adiponectin.	0.570