STRINGSTRING
Fgf12 Fgf12 CgPICR_012052 CgPICR_012052 I79_001024 I79_001024 Fgf23 Fgf23 I79_001364 I79_001364 Ntf3 Ntf3 Wnt5a Wnt5a Fgf17 Fgf17 Src Src Fgf20 Fgf20 Plek2 Plek2 Erbb2 Erbb2 I79_006679 I79_006679 Fgf13 Fgf13 Efna1 Efna1 CgPICR_019990 CgPICR_019990 Ephb1 Ephb1 Nrp2 Nrp2 Plek Plek Fgf1 Fgf1 Fgf22 Fgf22 Crkl Crkl Vegfc Vegfc Cdc42 Cdc42 Ephb2 Ephb2 Gdnf Gdnf Fgf14 Fgf14 Fgfr3 Fgfr3 Igf1r Igf1r I79_011712 I79_011712 Stat3 Stat3 Fgf16 Fgf16 Hgf Hgf Stat2 Stat2 I79_013907 I79_013907 Crk Crk Pdgfa Pdgfa Stat6 Stat6 Insr Insr Pik3c3 Pik3c3 Npm3 Npm3 Frs2 Frs2 Nrp1 Nrp1 Myf5 Myf5 Fgf21 Fgf21 Pdgfb Pdgfb Agrn Agrn Fgf3 Fgf3 Fgf4 Fgf4 CgPICR_017317 CgPICR_017317 Epo Epo Wnt1 Wnt1 I79_019149 I79_019149 Vegfb Vegfb Stat1 Stat1 Fgf7 Fgf7 I79_020968 I79_020968 I79_021125 I79_021125 Ereg Ereg I79_021151 I79_021151 Efnb1 Efnb1 I79_021577 I79_021577 Irs1 Irs1 Efna5 Efna5 Mtor Mtor Fgfr2 Fgfr2 Pdgfra Pdgfra I79_024975 I79_024975 I79_025433 I79_025433 I79_025496 I79_025496 I79_025497 I79_025497 I79_025518 I79_025518 I79_025535 I79_025535 I79_025726 I79_025726 I79_026231 I79_026231
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
I79_001024Ephrin-B2; Belongs to the ephrin family. (373 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
I79_001364Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
Ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (258 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (350 aa)
SrcTyrosine-protein kinase. (536 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
Plek2Pleckstrin-2. (339 aa)
Erbb2Receptor protein-tyrosine kinase. (1256 aa)
I79_006679Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (117 aa)
Efna1Ephrin-A1; Belongs to the ephrin family. (205 aa)
CgPICR_019990Persephin. (157 aa)
Ephb1Ephrin type-B receptor 1. (737 aa)
Nrp2Neuropilin; Belongs to the neuropilin family. (909 aa)
PlekPleckstrin. (327 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Fgf22Fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (70 aa)
CrklCrk-like protein. (303 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
Cdc42Cell division control protein 42-like. (191 aa)
Ephb2Ephrin type-B receptor 2. (1018 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Fgf14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
Stat2Signal transducer and activator of transcription. (806 aa)
I79_013907Ephrin-B2. (148 aa)
CrkProto-oncogene C-crk. (327 aa)
PdgfaPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (265 aa)
Stat6Signal transducer and activator of transcription. (844 aa)
InsrInsulin receptor. (114 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (822 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
Myf5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
AgrnAgrin. (2036 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
CgPICR_017317Insulin receptor substrate 1. (493 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
VegfbVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (150 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
I79_021125Epigen. (135 aa)
EregProepiregulin. (162 aa)
I79_021151Ephrin-B2. (178 aa)
Efnb1Ephrin-B1; Belongs to the ephrin family. (343 aa)
I79_021577Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (248 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
Efna5Ephrin-A5; Belongs to the ephrin family. (172 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
I79_024975Ephrin-B2. (148 aa)
I79_025433Ephrin-B2; Belongs to the ephrin family. (70 aa)
I79_025496Ephrin-B2. (147 aa)
I79_025497Ephrin-B2; Belongs to the ephrin family. (69 aa)
I79_025518Ephrin-B2. (123 aa)
I79_025535Ephrin-B2. (125 aa)
I79_025726Ephrin-B2. (121 aa)
I79_026231Ephrin-B2; Belongs to the ephrin family. (68 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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