node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bcan | H671_3g8622 | G3HG76 | G3HIA8 | Brevican core protein. | Semaphorin-4D; Belongs to the semaphorin family. | 0.404 |
Bcan | Omg | G3HG76 | G3GTR0 | Brevican core protein. | Oligodendrocyte-myelin glycoprotein. | 0.615 |
Bcan | Sema3a | G3HG76 | G3HN27 | Brevican core protein. | Semaphorin-3A-like protein; Belongs to the semaphorin family. | 0.508 |
Cntf | Gdnf | G3IIP9 | G3HJV8 | Ciliary neurotrophic factor. | Glial cell line-derived neurotrophic factor. | 0.877 |
Cntf | I79_015109 | G3IIP9 | G3HVW6 | Ciliary neurotrophic factor. | Interleukin-6. | 0.681 |
Cntf | I79_021577 | G3IIP9 | G3ID16 | Ciliary neurotrophic factor. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.840 |
Cntf | Igf1 | G3IIP9 | G3H672 | Ciliary neurotrophic factor. | Insulin-like growth factor I. | 0.663 |
Cntf | Lif | G3IIP9 | G3I136 | Ciliary neurotrophic factor. | Leukemia inhibitory factor-like protein. | 0.831 |
Cntf | Ntf3 | G3IIP9 | G3GUL2 | Ciliary neurotrophic factor. | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 0.656 |
Fgf1 | Gdnf | G3HEK8 | G3HJV8 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Glial cell line-derived neurotrophic factor. | 0.485 |
Fgf1 | I79_015109 | G3HEK8 | G3HVW6 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Interleukin-6. | 0.485 |
Fgf1 | I79_021577 | G3HEK8 | G3ID16 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.555 |
Fgf1 | Igf1 | G3HEK8 | G3H672 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Insulin-like growth factor I. | 0.740 |
Fgf1 | Lif | G3HEK8 | G3I136 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Leukemia inhibitory factor-like protein. | 0.540 |
Fgf1 | Ntf3 | G3HEK8 | G3GUL2 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 0.629 |
Gdnf | Cntf | G3HJV8 | G3IIP9 | Glial cell line-derived neurotrophic factor. | Ciliary neurotrophic factor. | 0.877 |
Gdnf | Fgf1 | G3HJV8 | G3HEK8 | Glial cell line-derived neurotrophic factor. | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | 0.485 |
Gdnf | I79_021577 | G3HJV8 | G3ID16 | Glial cell line-derived neurotrophic factor. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.900 |
Gdnf | I79_025433 | G3HJV8 | G3INB8 | Glial cell line-derived neurotrophic factor. | Ephrin-B2; Belongs to the ephrin family. | 0.507 |
Gdnf | Igf1 | G3HJV8 | G3H672 | Glial cell line-derived neurotrophic factor. | Insulin-like growth factor I. | 0.678 |