(13 nodes) (2015) Tetraspanins as therapeutic targets in hematological malignancy: a concise review. network (Cricetulus griseus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	Cd9	Tetraspanin. (159 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Cd82	Tetraspanin. (249 aa)
	Cxcr4	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
	Lck	Proto-oncogene tyrosine-protein kinase LCK. (158 aa)
	Il10	Interleukin-10. (178 aa)
	Syk	Tyrosine-protein kinase. (611 aa)
	Cd81	Tetraspanin. (236 aa)
	Lyn	Tyrosine-protein kinase. (289 aa)
	Cd151	CD151 antigen; Belongs to the tetraspanin (TM4SF) family. (266 aa)
	Cd53	Tetraspanin. (219 aa)
	Adam10	Disintegrin and metalloproteinase domain-containing protein 10. (675 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adam10	Cd81	G3GRM2	G3HXZ3	Disintegrin and metalloproteinase domain-containing protein 10.	Tetraspanin.	0.535
Adam10	Cd82	G3GRM2	G3GYG8	Disintegrin and metalloproteinase domain-containing protein 10.	Tetraspanin.	0.512
Adam10	Cd9	G3GRM2	G3GUL4	Disintegrin and metalloproteinase domain-containing protein 10.	Tetraspanin.	0.580
Cd151	Cd81	G3I3H4	G3HXZ3	CD151 antigen; Belongs to the tetraspanin (TM4SF) family.	Tetraspanin.	0.681
Cd151	Cd82	G3I3H4	G3GYG8	CD151 antigen; Belongs to the tetraspanin (TM4SF) family.	Tetraspanin.	0.467
Cd151	Cd9	G3I3H4	G3GUL4	CD151 antigen; Belongs to the tetraspanin (TM4SF) family.	Tetraspanin.	0.617
Cd4	Cd81	G3GUN9	G3HXZ3	T-cell surface glycoprotein CD4.	Tetraspanin.	0.813
Cd4	Cd82	G3GUN9	G3GYG8	T-cell surface glycoprotein CD4.	Tetraspanin.	0.725
Cd4	Cd9	G3GUN9	G3GUL4	T-cell surface glycoprotein CD4.	Tetraspanin.	0.810
Cd4	Cxcr4	G3GUN9	G3GZR2	T-cell surface glycoprotein CD4.	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family.	0.891
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Lck	G3GUN9	G3H943	T-cell surface glycoprotein CD4.	Proto-oncogene tyrosine-protein kinase LCK.	0.987
Cd4	Lyn	G3GUN9	G3I2D1	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.612
Cd4	Syk	G3GUN9	G3HIA4	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.754
Cd53	Cd82	G3IBU5	G3GYG8	Tetraspanin.	Tetraspanin.	0.546
Cd81	Adam10	G3HXZ3	G3GRM2	Tetraspanin.	Disintegrin and metalloproteinase domain-containing protein 10.	0.535
Cd81	Cd151	G3HXZ3	G3I3H4	Tetraspanin.	CD151 antigen; Belongs to the tetraspanin (TM4SF) family.	0.681
Cd81	Cd4	G3HXZ3	G3GUN9	Tetraspanin.	T-cell surface glycoprotein CD4.	0.813
Cd81	Cd82	G3HXZ3	G3GYG8	Tetraspanin.	Tetraspanin.	0.744