(35 nodes) (2015) Paracoccidioides-host Interaction: An Overview on Recent Advances in the Paracoccidioidomycosis. network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cdc42	Cell division control protein 42-like. (191 aa)
	CgPICR_013910	Glyceraldehyde-3-phosphate dehydrogenase. (104 aa)
	Casp2	Caspase-2; Belongs to the peptidase C14A family. (421 aa)
	CgPICR_000709	Glyceraldehyde-3-phosphate dehydrogenase. (148 aa)
	CgPICR_000710	Glyceraldehyde-3-phosphate dehydrogenase. (129 aa)
	CgPICR_020194	Glyceraldehyde-3-phosphate dehydrogenase. (105 aa)
	CgPICR_002764	Glyceraldehyde-3-phosphate dehydrogenase. (77 aa)
	I79_017439	Triosephosphate isomerase. (187 aa)
	Fn1	Fibronectin. (2486 aa)
	Pld1	Phospholipase D1. (175 aa)
	CgPICR_017546	Glyceraldehyde-3-phosphate dehydrogenase. (127 aa)
	CgPICR_002995	Glyceraldehyde-3-phosphate dehydrogenase. (206 aa)
	CgPICR_017739	Glyceraldehyde-3-phosphate dehydrogenase. (163 aa)
	Rho	Rhodopsin. (348 aa)
	CgPICR_017756	Calmodulin-like protein; Belongs to the calmodulin family. (98 aa)
	I79_012448	Triosephosphate isomerase. (150 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Casp8	Caspase-8; Belongs to the peptidase C14A family. (481 aa)
	I79_024941	Calmodulin; Belongs to the calmodulin family. (149 aa)
	CgPICR_008588	Glyceraldehyde-3-phosphate dehydrogenase. (161 aa)
	I79_022257	Actin. (98 aa)
	I79_021949	Caspase-3; Belongs to the peptidase C14A family. (195 aa)
	CgPICR_012401	Glyceraldehyde-3-phosphate dehydrogenase. (75 aa)
	I79_020786	Calmodulin; Belongs to the calmodulin family. (141 aa)
	Stpg4	Calmodulin; Belongs to the calmodulin family. (211 aa)
	I79_018847	Calmodulin; Belongs to the calmodulin family. (152 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Ctla4	Cytotoxic T-lymphocyte protein 4. (171 aa)
	I79_004996	Triosephosphate isomerase. (83 aa)
	I79_005936	Phospholipase D1. (688 aa)
	Il10	Interleukin-10. (178 aa)
	Calm2	Calmodulin; Belongs to the calmodulin family. (161 aa)
	Bcl2	Apoptosis regulator Bcl-2. (203 aa)
	I79_009796	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
	CgPICR_005523	Triosephosphate isomerase. (136 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcl2	Casp2	G3HD46	G3HL30	Apoptosis regulator Bcl-2.	Caspase-2; Belongs to the peptidase C14A family.	0.653
Bcl2	Casp8	G3HD46	B2CMK5	Apoptosis regulator Bcl-2.	Caspase-8; Belongs to the peptidase C14A family.	0.860
Bcl2	Cd4	G3HD46	G3GUN9	Apoptosis regulator Bcl-2.	T-cell surface glycoprotein CD4.	0.574
Bcl2	CgPICR_000709	G3HD46	G3HKA4	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_000710	G3HD46	G3HKA3	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_002764	G3HD46	G3HJV9	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_002995	G3HD46	G3HZA8	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_008588	G3HD46	G3IHS0	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_012401	G3HD46	G3ID55	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_013910	G3HD46	G3HN28	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_017546	G3HD46	G3I044	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_017739	G3HD46	G3HYZ4	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.538
Bcl2	CgPICR_020194	G3HD46	G3HK68	Apoptosis regulator Bcl-2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.532
Bcl2	I79_021949	G3HD46	G3IE08	Apoptosis regulator Bcl-2.	Caspase-3; Belongs to the peptidase C14A family.	0.938
Bcl2	I79_022257	G3HD46	G3IEV3	Apoptosis regulator Bcl-2.	Actin.	0.480
Bcl2	Ifng	G3HD46	G3GY20	Apoptosis regulator Bcl-2.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.478
Bcl2	Il10	G3HD46	G3HB01	Apoptosis regulator Bcl-2.	Interleukin-10.	0.500
Calm2	Cdc42	G3HBG8	G3HIM4	Calmodulin; Belongs to the calmodulin family.	Cell division control protein 42-like.	0.550
Calm2	I79_022257	G3HBG8	G3IEV3	Calmodulin; Belongs to the calmodulin family.	Actin.	0.702
Casp2	Bcl2	G3HL30	G3HD46	Caspase-2; Belongs to the peptidase C14A family.	Apoptosis regulator Bcl-2.	0.653