STRINGSTRING
Drosha Drosha Adam15 Adam15 Mcl1 Mcl1 I79_004417 I79_004417 Arhgap1 Arhgap1 I79_001600 I79_001600 Sfmbt2 Sfmbt2 Bak1 Bak1 I79_021949 I79_021949 Prkcb Prkcb AGO2 AGO2 I79_018057 I79_018057 Nras Nras I79_009500 I79_009500 Bcl2 Bcl2 Prkca Prkca
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DroshaRibonuclease 3. (1372 aa)
Adam15Disintegrin and metalloproteinase domain-containing protein 15. (844 aa)
Mcl1Putative induced myeloid leukemia cell differentiation protein Mcl-1 like protein. (120 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Arhgap1Rho GTPase-activating protein 1. (439 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Sfmbt2Scm-like with four MBT domains protein 2. (963 aa)
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
PrkcbNon-specific serine/threonine protein kinase. (544 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (813 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
NrasCold shock domain-containing protein E1. (451 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
PrkcaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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