STRINGSTRING
I79_016240 I79_016240 I79_018057 I79_018057 CgPICR_017737 CgPICR_017737 Cfl2 Cfl2 I79_001600 I79_001600 Ifnb1 Ifnb1 I79_004417 I79_004417 Erbb2 Erbb2 Rhoa Rhoa Bcl2 Bcl2 Lamp1 Lamp1 Becn1 Becn1 Clu Clu Xbp1 Xbp1 I79_021949 I79_021949 Cfl1 Cfl1 HSPA5 HSPA5 Atf6 Atf6 PPARG PPARG CgPICR_018851 CgPICR_018851
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_016240Beclin-1. (119 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
CgPICR_017737Lysosome-associated membrane glycoprotein 1. (403 aa)
Cfl2Cofilin-2; Belongs to the actin-binding proteins ADF family. (52 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Ifnb1Interferon beta. (182 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Erbb2Receptor protein-tyrosine kinase. (1256 aa)
RhoaTransforming protein RhoA. (193 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Lamp1Lysosome-associated membrane glycoprotein 1. (370 aa)
Becn1Beclin-1. (448 aa)
CluClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (447 aa)
Xbp1X-box binding protein 1 isoform 1. (330 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] (654 aa)
Atf6Cyclic AMP-dependent transcription factor ATF-6 alpha. (659 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
CgPICR_01885110 kDa heat shock protein, mitochondrial; Belongs to the GroES chaperonin family. (102 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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