(20 nodes) (2017) Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice. network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kit	Mast/stem cell growth factor receptor. (452 aa)
	Gfra1	GDNF family receptor alpha-1. (284 aa)
	I79_018852	Amino acid transporter. (158 aa)
	Zbtb16	Zinc finger and BTB domain-containing protein 16. (423 aa)
	Itgb1	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	Slc1a1	Amino acid transporter. (492 aa)
	Ccnd3	G1/S-specific cyclin-D3; Belongs to the cyclin family. (353 aa)
	Nanos2	Nanos-like 2; Belongs to the nanos family. (132 aa)
	Slc1a6	Amino acid transporter. (562 aa)
	Cdkn1a	Cyclin-dependent kinase inhibitor 1. (163 aa)
	Gdnf	Glial cell line-derived neurotrophic factor. (160 aa)
	Slc1a3	Amino acid transporter. (529 aa)
	Cdkn1b	Cyclin-dependent kinase inhibitor 1B. (198 aa)
	Neurog3	Neurogenin-3. (214 aa)
	Slc1a2	Amino acid transporter. (553 aa)
	Slc7a1	High affinity cationic amino acid transporter 1. (628 aa)
	Cd9	Tetraspanin. (159 aa)
	Ccnd2	G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa)
	I79_001019	Amino acid transporter. (596 aa)
	Ccnd1	G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccnd1	Ccnd2	A5A422	G3GUJ9	G1/S-specific cyclin-D1; Belongs to the cyclin family.	G1/S-specific cyclin-D2; Belongs to the cyclin family.	0.932
Ccnd1	Ccnd3	A5A422	G3HR48	G1/S-specific cyclin-D1; Belongs to the cyclin family.	G1/S-specific cyclin-D3; Belongs to the cyclin family.	0.932
Ccnd1	Cdkn1a	A5A422	G3HKC6	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1.	0.998
Ccnd1	Cdkn1b	A5A422	G3HB36	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1B.	0.998
Ccnd1	Kit	A5A422	G3IMP9	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Mast/stem cell growth factor receptor.	0.407
Ccnd2	Ccnd1	G3GUJ9	A5A422	G1/S-specific cyclin-D2; Belongs to the cyclin family.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.932
Ccnd2	Ccnd3	G3GUJ9	G3HR48	G1/S-specific cyclin-D2; Belongs to the cyclin family.	G1/S-specific cyclin-D3; Belongs to the cyclin family.	0.922
Ccnd2	Cdkn1a	G3GUJ9	G3HKC6	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1.	0.996
Ccnd2	Cdkn1b	G3GUJ9	G3HB36	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1B.	0.996
Ccnd3	Ccnd1	G3HR48	A5A422	G1/S-specific cyclin-D3; Belongs to the cyclin family.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.932
Ccnd3	Ccnd2	G3HR48	G3GUJ9	G1/S-specific cyclin-D3; Belongs to the cyclin family.	G1/S-specific cyclin-D2; Belongs to the cyclin family.	0.922
Ccnd3	Cdkn1a	G3HR48	G3HKC6	G1/S-specific cyclin-D3; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1.	0.997
Ccnd3	Cdkn1b	G3HR48	G3HB36	G1/S-specific cyclin-D3; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1B.	0.997
Ccnd3	Gdnf	G3HR48	G3HJV8	G1/S-specific cyclin-D3; Belongs to the cyclin family.	Glial cell line-derived neurotrophic factor.	0.423
Cd9	Itgb1	G3GUL4	G3HZ55	Tetraspanin.	Integrin beta; Belongs to the integrin beta chain family.	0.889
Cd9	Kit	G3GUL4	G3IMP9	Tetraspanin.	Mast/stem cell growth factor receptor.	0.526
Cdkn1a	Ccnd1	G3HKC6	A5A422	Cyclin-dependent kinase inhibitor 1.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.998
Cdkn1a	Ccnd2	G3HKC6	G3GUJ9	Cyclin-dependent kinase inhibitor 1.	G1/S-specific cyclin-D2; Belongs to the cyclin family.	0.996
Cdkn1a	Ccnd3	G3HKC6	G3HR48	Cyclin-dependent kinase inhibitor 1.	G1/S-specific cyclin-D3; Belongs to the cyclin family.	0.997
Cdkn1a	Cdkn1b	G3HKC6	G3HB36	Cyclin-dependent kinase inhibitor 1.	Cyclin-dependent kinase inhibitor 1B.	0.968