STRINGSTRING
Gcg Gcg Adipoq Adipoq I79_015980 I79_015980 Ins Ins Ppargc1a Ppargc1a Aanat Aanat Cry1 Cry1 Pklr Pklr Pkm Pkm Ghrl Ghrl Npy Npy Lep Lep Gcgr Gcgr I79_023874 I79_023874 I79_020755 I79_020755 I79_020424 I79_020424 Clock Clock Per2 Per2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GcgSeprase; Belongs to the peptidase S9B family. (561 aa)
AdipoqAdiponectin. (248 aa)
I79_015980Leptin receptor. (533 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
AanatSerotonin N-acetyltransferase. (207 aa)
Cry1Cryptochrome-1. (428 aa)
PklrPyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
GhrlAppetite-regulating hormone. (100 aa)
NpyNeuropeptide Y. (148 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
GcgrGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (486 aa)
I79_023874Pyruvate kinase; Belongs to the pyruvate kinase family. (233 aa)
I79_020755Pyruvate kinase; Belongs to the pyruvate kinase family. (461 aa)
I79_020424Pyruvate kinase; Belongs to the pyruvate kinase family. (258 aa)
ClockCircadian locomoter output cycles protein kaput. (599 aa)
Per2Period circadian protein-like 2. (1262 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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