(11 nodes) (2017) Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines. network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tlr3	Toll-like receptor 3. (164 aa)
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)
	I79_000639	Circumsporozoite protein. (113 aa)
	Tlr10	Toll-like receptor 10; Belongs to the Toll-like receptor family. (801 aa)
	Tlr7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	Il10	Interleukin-10. (178 aa)
	Cd86	T-lymphocyte activation antigen CD86. (269 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5. (118 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Lalba	Alpha-lactalbumin; Belongs to the glycosyl hydrolase 22 family. (123 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Cd40	G3GUN9	G3H8U5	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.949
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Cd86	G3GUN9	G3HAJ6	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD86.	0.955
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Tlr10	G3GUN9	G3IMP6	T-cell surface glycoprotein CD4.	Toll-like receptor 10; Belongs to the Toll-like receptor family.	0.659
Cd4	Tlr3	G3GUN9	G3IHU2	T-cell surface glycoprotein CD4.	Toll-like receptor 3.	0.905
Cd4	Tlr4	G3GUN9	G3I192	T-cell surface glycoprotein CD4.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.914
Cd4	Tlr7	G3GUN9	G3I9Z2	T-cell surface glycoprotein CD4.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.912
Cd40	Cd4	G3H8U5	G3GUN9	Tumor necrosis factor receptor superfamily member 5.	T-cell surface glycoprotein CD4.	0.949
Cd40	Cd80	G3H8U5	G3I1J7	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD80.	0.963
Cd40	Cd86	G3H8U5	G3HAJ6	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD86.	0.968
Cd40	Il10	G3H8U5	G3HB01	Tumor necrosis factor receptor superfamily member 5.	Interleukin-10.	0.858
Cd40	Tlr3	G3H8U5	G3IHU2	Tumor necrosis factor receptor superfamily member 5.	Toll-like receptor 3.	0.581
Cd40	Tlr4	G3H8U5	G3I192	Tumor necrosis factor receptor superfamily member 5.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.841
Cd40	Tlr7	G3H8U5	G3I9Z2	Tumor necrosis factor receptor superfamily member 5.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.617
Cd80	Cd4	G3I1J7	G3GUN9	T-lymphocyte activation antigen CD80.	T-cell surface glycoprotein CD4.	0.964
Cd80	Cd40	G3I1J7	G3H8U5	T-lymphocyte activation antigen CD80.	Tumor necrosis factor receptor superfamily member 5.	0.963
Cd80	Cd86	G3I1J7	G3HAJ6	T-lymphocyte activation antigen CD80.	T-lymphocyte activation antigen CD86.	0.997
Cd80	Il10	G3I1J7	G3HB01	T-lymphocyte activation antigen CD80.	Interleukin-10.	0.868
Cd80	Tlr3	G3I1J7	G3IHU2	T-lymphocyte activation antigen CD80.	Toll-like receptor 3.	0.648