(21 nodes) (2017) MUC1: The First Respiratory Mucin with an Anti-Inflammatory Function. network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	Irak1	Interleukin-1 receptor-associated kinase 1. (494 aa)
	I79_013395	Matrix metalloproteinase-14. (539 aa)
	Elane	Neutrophil elastase; Belongs to the peptidase S1 family. (252 aa)
	Gsk3b	Glycogen synthase kinase-3 beta. (328 aa)
	Csf2	Granulocyte-macrophage colony-stimulating factor. (95 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
	Tlr5	Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
	Tlr9	Toll-like receptor 9. (1239 aa)
	Traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	Ifnb1	Interferon beta. (182 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	CgPICR_012052	Growth factor receptor-bound protein 2. (217 aa)
	Tlr6	Toll-like receptor. (795 aa)
	Tlr3	Toll-like receptor 3. (164 aa)
	CgPICR_017379	Toll-like receptor 11. (916 aa)
	Ereg	Proepiregulin. (162 aa)
	Tlr7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
	Agrn	Agrin. (2036 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Agrn	I79_013395	G3I437	G3HRD0	Agrin.	Matrix metalloproteinase-14.	0.457
Cd4	CgPICR_012052	G3GUN9	G3GTE4	T-cell surface glycoprotein CD4.	Growth factor receptor-bound protein 2.	0.526
Cd4	CgPICR_017379	G3GUN9	G3IFP1	T-cell surface glycoprotein CD4.	Toll-like receptor 11.	0.833
Cd4	Csf2	G3GUN9	G3H567	T-cell surface glycoprotein CD4.	Granulocyte-macrophage colony-stimulating factor.	0.856
Cd4	Elane	G3GUN9	G3HF49	T-cell surface glycoprotein CD4.	Neutrophil elastase; Belongs to the peptidase S1 family.	0.525
Cd4	IL2	G3GUN9	G3HTL8	T-cell surface glycoprotein CD4.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.974
Cd4	Ifnb1	G3GUN9	G3GXU9	T-cell surface glycoprotein CD4.	Interferon beta.	0.719
Cd4	Irak1	G3GUN9	G3HSV4	T-cell surface glycoprotein CD4.	Interleukin-1 receptor-associated kinase 1.	0.500
Cd4	PPARG	G3GUN9	G3HVG0	T-cell surface glycoprotein CD4.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.669
Cd4	Tlr3	G3GUN9	G3IHU2	T-cell surface glycoprotein CD4.	Toll-like receptor 3.	0.905
Cd4	Tlr4	G3GUN9	G3I192	T-cell surface glycoprotein CD4.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.914
Cd4	Tlr5	G3GUN9	G3GRB7	T-cell surface glycoprotein CD4.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.784
Cd4	Tlr6	G3GUN9	G3INL2	T-cell surface glycoprotein CD4.	Toll-like receptor.	0.880
Cd4	Tlr7	G3GUN9	G3I9Z2	T-cell surface glycoprotein CD4.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.912
Cd4	Tlr9	G3GUN9	G3GZG1	T-cell surface glycoprotein CD4.	Toll-like receptor 9.	0.889
Cd4	Tnf	G3GUN9	G3HZG9	T-cell surface glycoprotein CD4.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.884
Cd4	Traf6	G3GUN9	G3GZ05	T-cell surface glycoprotein CD4.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.740
CgPICR_012052	Cd4	G3GTE4	G3GUN9	Growth factor receptor-bound protein 2.	T-cell surface glycoprotein CD4.	0.526
CgPICR_012052	Ereg	G3GTE4	G3IBU3	Growth factor receptor-bound protein 2.	Proepiregulin.	0.535
CgPICR_012052	Gsk3b	G3GTE4	G3HAI0	Growth factor receptor-bound protein 2.	Glycogen synthase kinase-3 beta.	0.445