STRINGSTRING
Becn1 Becn1 Casp8 Casp8 I79_001600 I79_001600 Src Src Ctsb Ctsb I79_004417 I79_004417 Bcl2 Bcl2 Egr1 Egr1 Rtn4 Rtn4 Atf6 Atf6 Atg5 Atg5 I79_016240 I79_016240 I79_017574 I79_017574 I79_018057 I79_018057 Anxa5 Anxa5 I79_020089 I79_020089 Alb Alb I79_021949 I79_021949 Mtor Mtor I79_023773 I79_023773 I79_025220 I79_025220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Becn1Beclin-1. (448 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
SrcTyrosine-protein kinase. (536 aa)
CtsbCathepsin B; Belongs to the peptidase C1 family. (339 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa)
Rtn4Reticulon-4. (806 aa)
Atf6Cyclic AMP-dependent transcription factor ATF-6 alpha. (659 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (147 aa)
I79_016240Beclin-1. (119 aa)
I79_017574Caspase-12; Belongs to the peptidase C14A family. (729 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Anxa5Annexin. (321 aa)
I79_020089Caspase-9; Belongs to the peptidase C14A family. (689 aa)
AlbSerum albumin. (430 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_023773Nuclear receptor subfamily 4 group A member 1. (924 aa)
I79_025220Serum albumin. (186 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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