STRINGSTRING
Fgf7 Fgf7 Efnb1 Efnb1 Cfl1 Cfl1 Efna5 Efna5 I79_022257 I79_022257 Celsr1 Celsr1 Prickle1 Prickle1 Alx3 Alx3 Abl1 Abl1 Folr1 Folr1 I79_024393 I79_024393 Wnt9b Wnt9b SLC19A1 SLC19A1 Fgf13 Fgf13 Dlx5 Dlx5 I79_008485 I79_008485 Fgf1 Fgf1 Sfrp1 Sfrp1 Cdc42 Cdc42 Evl Evl Pak4 Pak4 Fgf14 Fgf14 Fzd1 Fzd1 Myo10 Myo10 Intu Intu Grhl3 Grhl3 Prickle3 Prickle3 Fgf16 Fgf16 Mapk9 Mapk9 Vasp Vasp Tcf7l1 Tcf7l1 Ttc21b Ttc21b Invs Invs Smad4 Smad4 Wnt11 Wnt11 Gli3 Gli3 Fat1 Fat1 Abl2 Abl2 Scarb1 Scarb1 Rab23 Rab23 Npm3 Npm3 Sufu Sufu Smurf1 Smurf1 Fgf21 Fgf21 Prickle4 Prickle4 Cnot1 Cnot1 Fat4 Fat4 Mthfd2 Mthfd2 Fgf3 Fgf3 Fgf4 Fgf4 Epha5 Epha5 Wnt1 Wnt1 I79_019149 I79_019149 Epha2 Epha2 Lhx2 Lhx2 C2cd3 C2cd3 Fgf12 Fgf12 Mthfd1l Mthfd1l Tbx3 Tbx3 Tulp3 Tulp3 Fgf23 Fgf23 I79_001364 I79_001364 Wnt5a Wnt5a Dync2h1 Dync2h1 Fgf17 Fgf17 Vcl Vcl Arl13b Arl13b Smo Smo Fgf20 Fgf20 Fzd3 Fzd3 Msx2 Msx2 I79_004731 I79_004731 I79_004732 I79_004732 Septin2 Septin2 Sall1 Sall1 Vangl2 Vangl2 Inka1 Inka1 Rhoa Rhoa Prickle2 Prickle2 I79_006679 I79_006679 Nuak2 Nuak2 Lrp6 Lrp6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Efnb1Ephrin-B1; Belongs to the ephrin family. (343 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
Efna5Ephrin-A5; Belongs to the ephrin family. (172 aa)
I79_022257Actin. (98 aa)
Celsr1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1009 aa)
Prickle1Prickle-like protein 1. (619 aa)
Alx3Homeobox protein aristaless-like 3. (200 aa)
Abl1Tyrosine-protein kinase transforming protein Abl. (322 aa)
Folr1Folate receptor alpha. (257 aa)
I79_024393Cofilin-1. (85 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
SLC19A1Reduced folate transporter; Transporter that mediates the import of reduced folates. Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate. Also able to mediate the import of antifolate drug methotrexate. Mechanistically, acts as an antiporter, which export of intracellular organic anions to facilitate uptake of its substrates. 5-amino-4-imidazolecarboxamide riboside (AICAR), when phosphorylated to AICAR monophosphate, can serve as an organic anion for antiporter activity. (518 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (117 aa)
Dlx5Homeobox protein DLX-5. (289 aa)
I79_008485Cofilin-1; Belongs to the actin-binding proteins ADF family. (111 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
Cdc42Cell division control protein 42-like. (191 aa)
EvlEna/VASP-like protein. (371 aa)
Pak4Non-specific serine/threonine protein kinase. (588 aa)
Fgf14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
Myo10Myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1422 aa)
IntuPDZ domain-containing protein 6. (938 aa)
Grhl3Grainyhead-like protein 3-like. (596 aa)
Prickle3Prickle-like protein 3. (181 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
Mapk9Mitogen-activated protein kinase 9. (303 aa)
VaspVasodilator-stimulated phosphoprotein. (129 aa)
Tcf7l1Transcription factor 7-like 1. (297 aa)
Ttc21bTetratricopeptide repeat protein 21B. (1315 aa)
InvsInversin. (1054 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Fat1Protocadherin Fat 1. (4589 aa)
Abl2Tyrosine-protein kinase. (1167 aa)
Scarb1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
Rab23Ras-related protein Rab-23. (236 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
SufuSuppressor of fused-like. (266 aa)
Smurf1E3 ubiquitin-protein ligase SMURF1. (303 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
Prickle4Prickle-like protein 4. (219 aa)
Cnot1CCR4-NOT transcription complex subunit 1. (1520 aa)
Fat4Protocadherin Fat 4. (5152 aa)
Mthfd2Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial. (350 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
Epha5Ephrin type-A receptor 5. (556 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Epha2Ephrin type-A receptor 2. (942 aa)
Lhx2LIM/homeobox protein Lhx2. (385 aa)
C2cd3C2 domain-containing protein 3. (2233 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
Mthfd1lMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (975 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
Tulp3Tubby-like protein; Belongs to the TUB family. (414 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
I79_001364Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Dync2h1Cytoplasmic dynein 2 heavy chain 1. (117 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (350 aa)
VclVinculin. (1143 aa)
Arl13bADP-ribosylation factor-like protein 13B. (422 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Msx2Homeobox protein MSX-2. (267 aa)
I79_004731Palladin. (311 aa)
I79_004732Palladin. (379 aa)
Septin2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (321 aa)
Sall1Sal-like protein 1. (1294 aa)
Vangl2Vang-like protein. (521 aa)
Inka1Uncharacterized protein C3orf54-like. (283 aa)
RhoaTransforming protein RhoA. (193 aa)
Prickle2Prickle-like protein 2. (845 aa)
I79_006679Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
Nuak2NUAK family SNF1-like kinase 2. (297 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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