(9 nodes) (2018) Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy. network (Cricetulus griseus)

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Predicted Interactions

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Your Input:
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Src	Tyrosine-protein kinase. (536 aa)
	Foxp3	Forkhead box protein P3. (428 aa)
	Ctla4	Cytotoxic T-lymphocyte protein 4. (171 aa)
	I79_025220	Serum albumin. (186 aa)
	I79_021949	Caspase-3; Belongs to the peptidase C14A family. (195 aa)
	Alb	Serum albumin. (430 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alb	Cd4	G3IAL6	G3GUN9	Serum albumin.	T-cell surface glycoprotein CD4.	0.860
Alb	Foxp3	G3IAL6	G3HNB1	Serum albumin.	Forkhead box protein P3.	0.426
Alb	I79_021949	G3IAL6	G3IE08	Serum albumin.	Caspase-3; Belongs to the peptidase C14A family.	0.695
Alb	I79_025220	G3IAL6	G3IMS5	Serum albumin.	Serum albumin.	0.960
Alb	IL2	G3IAL6	G3HTL8	Serum albumin.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.547
Alb	Ifng	G3IAL6	G3GY20	Serum albumin.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.749
Alb	Src	G3IAL6	G3GXX7	Serum albumin.	Tyrosine-protein kinase.	0.443
Cd4	Alb	G3GUN9	G3IAL6	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	Ctla4	G3GUN9	G3GYW4	T-cell surface glycoprotein CD4.	Cytotoxic T-lymphocyte protein 4.	0.962
Cd4	Foxp3	G3GUN9	G3HNB1	T-cell surface glycoprotein CD4.	Forkhead box protein P3.	0.966
Cd4	I79_021949	G3GUN9	G3IE08	T-cell surface glycoprotein CD4.	Caspase-3; Belongs to the peptidase C14A family.	0.805
Cd4	I79_025220	G3GUN9	G3IMS5	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	IL2	G3GUN9	G3HTL8	T-cell surface glycoprotein CD4.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.974
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Src	G3GUN9	G3GXX7	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.840
Ctla4	Cd4	G3GYW4	G3GUN9	Cytotoxic T-lymphocyte protein 4.	T-cell surface glycoprotein CD4.	0.962
Ctla4	Foxp3	G3GYW4	G3HNB1	Cytotoxic T-lymphocyte protein 4.	Forkhead box protein P3.	0.920
Ctla4	IL2	G3GYW4	G3HTL8	Cytotoxic T-lymphocyte protein 4.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.891
Ctla4	Ifng	G3GYW4	G3GY20	Cytotoxic T-lymphocyte protein 4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.889
Ctla4	Src	G3GYW4	G3GXX7	Cytotoxic T-lymphocyte protein 4.	Tyrosine-protein kinase.	0.517