(20 nodes) (2019) SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology. network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_025220	Serum albumin. (186 aa)
	Sorcs3	Sortilin. (249 aa)
	I79_001019	Amino acid transporter. (596 aa)
	I79_022257	Actin. (98 aa)
	Alb	Serum albumin. (430 aa)
	I79_019878	Sortilin. (1038 aa)
	I79_018852	Amino acid transporter. (158 aa)
	I79_015170	Beta-galactosidase. (615 aa)
	Slc1a1	Amino acid transporter. (492 aa)
	Syp	Synaptophysin. (310 aa)
	Slc1a6	Amino acid transporter. (562 aa)
	Gfap	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (427 aa)
	Slc1a3	Amino acid transporter. (529 aa)
	Pxdn	Peroxidasin-like. (1475 aa)
	Glb1	Beta-galactosidase. (650 aa)
	Slc1a2	Amino acid transporter. (553 aa)
	Sorcs2	VPS10 domain-containing receptor SorCS2. (985 aa)
	Actb	Actin, cytoplasmic 1. (375 aa)
	I79_001093	Beta-galactosidase. (659 aa)
	I79_001092	Beta-galactosidase. (680 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Actb	Alb	G3GVD0	G3IAL6	Actin, cytoplasmic 1.	Serum albumin.	0.525
Actb	Gfap	G3GVD0	G3HLL7	Actin, cytoplasmic 1.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.480
Actb	I79_025220	G3GVD0	G3IMS5	Actin, cytoplasmic 1.	Serum albumin.	0.525
Actb	Pxdn	G3GVD0	G3HBI1	Actin, cytoplasmic 1.	Peroxidasin-like.	0.574
Alb	Actb	G3IAL6	G3GVD0	Serum albumin.	Actin, cytoplasmic 1.	0.525
Alb	Gfap	G3IAL6	G3HLL7	Serum albumin.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.578
Alb	I79_022257	G3IAL6	G3IEV3	Serum albumin.	Actin.	0.738
Alb	I79_025220	G3IAL6	G3IMS5	Serum albumin.	Serum albumin.	0.960
Alb	Pxdn	G3IAL6	G3HBI1	Serum albumin.	Peroxidasin-like.	0.929
Gfap	Actb	G3HLL7	G3GVD0	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Actin, cytoplasmic 1.	0.480
Gfap	Alb	G3HLL7	G3IAL6	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Serum albumin.	0.578
Gfap	I79_025220	G3HLL7	G3IMS5	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Serum albumin.	0.578
Gfap	Pxdn	G3HLL7	G3HBI1	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Peroxidasin-like.	0.777
Gfap	Slc1a2	G3HLL7	G3GYZ2	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Amino acid transporter.	0.571
Gfap	Slc1a3	G3HLL7	G3HJU8	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Amino acid transporter.	0.423
Gfap	Syp	G3HLL7	G3HNB5	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Synaptophysin.	0.692
I79_022257	Alb	G3IEV3	G3IAL6	Actin.	Serum albumin.	0.738
I79_022257	I79_025220	G3IEV3	G3IMS5	Actin.	Serum albumin.	0.738
I79_022257	Pxdn	G3IEV3	G3HBI1	Actin.	Peroxidasin-like.	0.709
I79_025220	Actb	G3IMS5	G3GVD0	Serum albumin.	Actin, cytoplasmic 1.	0.525