(18 nodes) (2019) Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment. network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_021151	Ephrin-B2. (178 aa)
	I79_001024	Ephrin-B2; Belongs to the ephrin family. (373 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Tp53	Cellular tumor antigen p53. (148 aa)
	Kras	GTPase KRas. (155 aa)
	Foxp3	Forkhead box protein P3. (428 aa)
	I79_013907	Ephrin-B2. (148 aa)
	Smad4	Mothers against decapentaplegic-like 4. (259 aa)
	Ins	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
	Hras	GTPase HRas-like protein. (189 aa)
	I79_024975	Ephrin-B2. (148 aa)
	I79_025433	Ephrin-B2; Belongs to the ephrin family. (70 aa)
	I79_025496	Ephrin-B2. (147 aa)
	I79_025497	Ephrin-B2; Belongs to the ephrin family. (69 aa)
	I79_025518	Ephrin-B2. (123 aa)
	I79_025535	Ephrin-B2. (125 aa)
	I79_025726	Ephrin-B2. (121 aa)
	I79_026231	Ephrin-B2; Belongs to the ephrin family. (68 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Foxp3	G3GUN9	G3HNB1	T-cell surface glycoprotein CD4.	Forkhead box protein P3.	0.966
Cd4	Ins	G3GUN9	G3HXZ8	T-cell surface glycoprotein CD4.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.835
Cd4	Kras	G3GUN9	G3H3C9	T-cell surface glycoprotein CD4.	GTPase KRas.	0.421
Cd4	Tp53	G3GUN9	G3GY68	T-cell surface glycoprotein CD4.	Cellular tumor antigen p53.	0.601
Foxp3	Cd4	G3HNB1	G3GUN9	Forkhead box protein P3.	T-cell surface glycoprotein CD4.	0.966
Foxp3	Ins	G3HNB1	G3HXZ8	Forkhead box protein P3.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.407
Hras	Ins	G3I3F4	G3HXZ8	GTPase HRas-like protein.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.416
Hras	Kras	G3I3F4	G3H3C9	GTPase HRas-like protein.	GTPase KRas.	0.923
Hras	Tp53	G3I3F4	G3GY68	GTPase HRas-like protein.	Cellular tumor antigen p53.	0.635
I79_025433	I79_025518	G3INB8	G3INJ3	Ephrin-B2; Belongs to the ephrin family.	Ephrin-B2.	0.451
I79_025433	I79_026231	G3INB8	G3IQC0	Ephrin-B2; Belongs to the ephrin family.	Ephrin-B2; Belongs to the ephrin family.	0.495
I79_025518	I79_025433	G3INJ3	G3INB8	Ephrin-B2.	Ephrin-B2; Belongs to the ephrin family.	0.451
I79_026231	I79_025433	G3IQC0	G3INB8	Ephrin-B2; Belongs to the ephrin family.	Ephrin-B2; Belongs to the ephrin family.	0.495
Ins	Cd4	G3HXZ8	G3GUN9	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	T-cell surface glycoprotein CD4.	0.835
Ins	Foxp3	G3HXZ8	G3HNB1	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	Forkhead box protein P3.	0.407
Ins	Hras	G3HXZ8	G3I3F4	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	GTPase HRas-like protein.	0.416
Ins	Kras	G3HXZ8	G3H3C9	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	GTPase KRas.	0.413
Ins	Smad4	G3HXZ8	G3HTR4	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	Mothers against decapentaplegic-like 4.	0.420
Ins	Tp53	G3HXZ8	G3GY68	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	Cellular tumor antigen p53.	0.491
Kras	Cd4	G3H3C9	G3GUN9	GTPase KRas.	T-cell surface glycoprotein CD4.	0.421