(11 nodes) (2020) Comparison of Clinically Relevant Oncolytic Virus Platforms for Enhancing T Cell Therapy of Solid Tumors. network (Cricetulus griseus)

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second shell of interactors

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Your Input:
	Hck	Tyrosine-protein kinase. (503 aa)
	Il10	Interleukin-10. (178 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5. (118 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Ifngr1	Interferon-gamma receptor alpha chain. (471 aa)
	Tlr9	Toll-like receptor 9. (1239 aa)
	Casp8	Caspase-8; Belongs to the peptidase C14A family. (481 aa)
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	Ins	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
	Syk	Tyrosine-protein kinase. (611 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Casp8	Cd4	B2CMK5	G3GUN9	Caspase-8; Belongs to the peptidase C14A family.	T-cell surface glycoprotein CD4.	0.696
Casp8	IL1B	B2CMK5	G3I1B0	Caspase-8; Belongs to the peptidase C14A family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.787
Casp8	Syk	B2CMK5	G3HIA4	Caspase-8; Belongs to the peptidase C14A family.	Tyrosine-protein kinase.	0.518
Cd4	Casp8	G3GUN9	B2CMK5	T-cell surface glycoprotein CD4.	Caspase-8; Belongs to the peptidase C14A family.	0.696
Cd4	Cd40	G3GUN9	G3H8U5	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.949
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Hck	G3GUN9	G3HE98	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.709
Cd4	IL1B	G3GUN9	G3I1B0	T-cell surface glycoprotein CD4.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.872
Cd4	Ifngr1	G3GUN9	G3GW63	T-cell surface glycoprotein CD4.	Interferon-gamma receptor alpha chain.	0.587
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Ins	G3GUN9	G3HXZ8	T-cell surface glycoprotein CD4.	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family.	0.835
Cd4	Syk	G3GUN9	G3HIA4	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.754
Cd4	Tlr9	G3GUN9	G3GZG1	T-cell surface glycoprotein CD4.	Toll-like receptor 9.	0.889
Cd40	Cd4	G3H8U5	G3GUN9	Tumor necrosis factor receptor superfamily member 5.	T-cell surface glycoprotein CD4.	0.949
Cd40	Cd80	G3H8U5	G3I1J7	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD80.	0.963
Cd40	IL1B	G3H8U5	G3I1B0	Tumor necrosis factor receptor superfamily member 5.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.599
Cd40	Il10	G3H8U5	G3HB01	Tumor necrosis factor receptor superfamily member 5.	Interleukin-10.	0.858
Cd40	Syk	G3H8U5	G3HIA4	Tumor necrosis factor receptor superfamily member 5.	Tyrosine-protein kinase.	0.463
Cd40	Tlr9	G3H8U5	G3GZG1	Tumor necrosis factor receptor superfamily member 5.	Toll-like receptor 9.	0.707
Cd80	Cd4	G3I1J7	G3GUN9	T-lymphocyte activation antigen CD80.	T-cell surface glycoprotein CD4.	0.964