(58 nodes) (2020) TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein. network (Cricetulus griseus)

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second shell of interactors

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Your Input:
	Zcchc17	Nucleolar protein of 40 kDa. (233 aa)
	Traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
	Nop58	Nucleolar protein 58. (309 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Nup153	Nuclear pore complex protein Nup153. (1326 aa)
	Ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
	CgPICR_011571	60S ribosomal protein L19. (114 aa)
	Ubxn1	UBX domain-containing protein 1. (122 aa)
	Tifa	TRAF-interacting protein with FHA domain-containing protein A. (185 aa)
	Ubfd1	Ubiquitin domain-containing protein UBFD1. (182 aa)
	Stx5	Syntaxin-5; Belongs to the syntaxin family. (170 aa)
	CgPICR_008588	Glyceraldehyde-3-phosphate dehydrogenase. (161 aa)
	Rpl34	60S ribosomal protein L34. (137 aa)
	Anxa2	Annexin. (244 aa)
	Hspa8	Heat shock cognate 71 kDa protein. (237 aa)
	CgPICR_012401	Glyceraldehyde-3-phosphate dehydrogenase. (75 aa)
	Bag3	BAG family molecular chaperone regulator 3. (571 aa)
	Psmd10	26S proteasome non-ATPase regulatory subunit 10. (218 aa)
	CgPICR_019042	60S ribosomal protein L19. (75 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	CgPICR_017546	Glyceraldehyde-3-phosphate dehydrogenase. (127 aa)
	Vps4a	Vacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (437 aa)
	Rpl18	60S ribosomal protein L18. (136 aa)
	CgPICR_002995	Glyceraldehyde-3-phosphate dehydrogenase. (206 aa)
	CgPICR_017739	Glyceraldehyde-3-phosphate dehydrogenase. (163 aa)
	Tmed2	Transmembrane emp24 domain-containing protein 2. (116 aa)
	Trim26	Tripartite motif-containing protein 26 isoform 2. (540 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
	CgPICR_018283	40S ribosomal protein S6. (115 aa)
	Irak1	Interleukin-1 receptor-associated kinase 1. (494 aa)
	Mybbp1a	Myb-binding protein 1A. (932 aa)
	Brd2	Bromodomain-containing protein 2. (752 aa)
	Vamp8	Vesicle-associated membrane protein 8. (101 aa)
	Tbp	TATA-box-binding protein. (315 aa)
	CgPICR_013910	Glyceraldehyde-3-phosphate dehydrogenase. (104 aa)
	Ubr5	E3 ubiquitin-protein ligase UBR5. (380 aa)
	CgPICR_000709	Glyceraldehyde-3-phosphate dehydrogenase. (148 aa)
	CgPICR_000710	Glyceraldehyde-3-phosphate dehydrogenase. (129 aa)
	CgPICR_020194	Glyceraldehyde-3-phosphate dehydrogenase. (105 aa)
	CgPICR_002764	Glyceraldehyde-3-phosphate dehydrogenase. (77 aa)
	Rab12	Ras-related protein Rab-12. (170 aa)
	CgPICR_006951	60S ribosomal protein L4. (204 aa)
	Ipo13	Importin-13. (963 aa)
	CgPICR_013865	40S ribosomal protein S6-like protein. (141 aa)
	Abt1	Activator of basal transcription 1. (273 aa)
	Vps4b	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (436 aa)
	Ddx39a	ATP-dependent RNA helicase DDX39. (424 aa)
	Pxdn	Peroxidasin-like. (1475 aa)
	ENY2	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (131 aa)
	CgPICR_017031	40S ribosomal protein S6. (158 aa)
	Sirt1	NAD-dependent deacetylase sirtuin-1. (554 aa)
	Herc4	Putative E3 ubiquitin-protein ligase HERC4. (835 aa)
	Trappc3	Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (180 aa)
	Lsm6	U6 snRNA-associated Sm-like protein LSm6. (80 aa)
	Rpl4	Lactase-like protein; Belongs to the glycosyl hydrolase 1 family. (477 aa)
	Hsp90aa1	Heat shock protein HSP 90-alpha. (332 aa)
	Sf3b4	Splicing factor 3B subunit 4-like protein. (424 aa)
	Nhp2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abt1	Brd2	G3HDR8	G3HQS5	Activator of basal transcription 1.	Bromodomain-containing protein 2.	0.612
Abt1	Ddx39a	G3HDR8	G3HD18	Activator of basal transcription 1.	ATP-dependent RNA helicase DDX39.	0.548
Abt1	Lsm6	G3HDR8	G3H9H3	Activator of basal transcription 1.	U6 snRNA-associated Sm-like protein LSm6.	0.757
Abt1	Mybbp1a	G3HDR8	G3HSA2	Activator of basal transcription 1.	Myb-binding protein 1A.	0.744
Abt1	Nhp2	G3HDR8	G3H2E1	Activator of basal transcription 1.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.698
Abt1	Nop58	G3HDR8	G3GYX2	Activator of basal transcription 1.	Nucleolar protein 58.	0.810
Abt1	Sf3b4	G3HDR8	G3H2U6	Activator of basal transcription 1.	Splicing factor 3B subunit 4-like protein.	0.449
Abt1	Tifa	G3HDR8	G3IJM1	Activator of basal transcription 1.	TRAF-interacting protein with FHA domain-containing protein A.	0.476
Abt1	Zcchc17	G3HDR8	G3H1W9	Activator of basal transcription 1.	Nucleolar protein of 40 kDa.	0.510
Anxa2	Tlr4	G3IG05	G3I192	Annexin.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.634
Bag3	Hsp90aa1	G3ICC2	G3H354	BAG family molecular chaperone regulator 3.	Heat shock protein HSP 90-alpha.	0.682
Bag3	Hspa8	G3ICC2	G3IDC2	BAG family molecular chaperone regulator 3.	Heat shock cognate 71 kDa protein.	0.859
Bag3	Psmd10	G3ICC2	G3IC31	BAG family molecular chaperone regulator 3.	26S proteasome non-ATPase regulatory subunit 10.	0.455
Bag3	Rab12	G3ICC2	G3HIU9	BAG family molecular chaperone regulator 3.	Ras-related protein Rab-12.	0.408
Bag3	Ubfd1	G3ICC2	G3IIV0	BAG family molecular chaperone regulator 3.	Ubiquitin domain-containing protein UBFD1.	0.568
Brd2	Abt1	G3HQS5	G3HDR8	Bromodomain-containing protein 2.	Activator of basal transcription 1.	0.612
Brd2	ENY2	G3HQS5	G3HAU8	Bromodomain-containing protein 2.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	0.560
Brd2	Lsm6	G3HQS5	G3H9H3	Bromodomain-containing protein 2.	U6 snRNA-associated Sm-like protein LSm6.	0.604
Brd2	Mybbp1a	G3HQS5	G3HSA2	Bromodomain-containing protein 2.	Myb-binding protein 1A.	0.569
Brd2	Nhp2	G3HQS5	G3H2E1	Bromodomain-containing protein 2.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.437