STRINGSTRING
Vegfc Vegfc I79_000092 I79_000092 I79_001024 I79_001024 Bmpr2 Bmpr2 Cxcr4 Cxcr4 Igf1 Igf1 I79_006254 I79_006254 I79_007548 I79_007548 I79_008304 I79_008304 Nrp2 Nrp2 Tgfb3 Tgfb3 Acvr1 Acvr1 Akt2 Akt2 Runx1 Runx1 Pdk3 Pdk3 Aplnr Aplnr I79_013907 I79_013907 Pdk4 Pdk4 Nrp1 Nrp1 Dmd Dmd I79_016980 I79_016980 Lif Lif Fgf4 Fgf4 Epo Epo Klf4 Klf4 I79_021151 I79_021151 I79_021283 I79_021283 Dll4 Dll4 Cd34 Cd34 I79_022161 I79_022161 I79_024975 I79_024975 I79_025433 I79_025433 I79_025496 I79_025496 I79_025497 I79_025497 I79_025518 I79_025518 I79_025535 I79_025535 I79_025726 I79_025726 I79_026231 I79_026231
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
I79_001024Ephrin-B2; Belongs to the ephrin family. (373 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_007548Angiopoietin-1. (112 aa)
I79_008304Platelet endothelial cell adhesion molecule. (596 aa)
Nrp2Neuropilin; Belongs to the neuropilin family. (909 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Runx1Runt-related transcription factor 1. (462 aa)
Pdk3Protein-serine/threonine kinase. (415 aa)
AplnrApelin receptor; Belongs to the G-protein coupled receptor 1 family. (377 aa)
I79_013907Ephrin-B2. (148 aa)
Pdk4Protein-serine/threonine kinase. (178 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
DmdDystrophin. (617 aa)
I79_016980Dystrophin. (193 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
Klf4Krueppel-like factor 4. (474 aa)
I79_021151Ephrin-B2. (178 aa)
I79_021283Angiopoietin-1. (298 aa)
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
Cd34Hematopoietic progenitor cell antigen CD34. (383 aa)
I79_022161Dystrophin. (655 aa)
I79_024975Ephrin-B2. (148 aa)
I79_025433Ephrin-B2; Belongs to the ephrin family. (70 aa)
I79_025496Ephrin-B2. (147 aa)
I79_025497Ephrin-B2; Belongs to the ephrin family. (69 aa)
I79_025518Ephrin-B2. (123 aa)
I79_025535Ephrin-B2. (125 aa)
I79_025726Ephrin-B2. (121 aa)
I79_026231Ephrin-B2; Belongs to the ephrin family. (68 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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