(41 nodes) (2021) Phosphoproteomic Analysis of Subcutaneous and Omental Adipose Tissue Reveals Increased Lipid Turnover in Dairy Cows Supplemented with Conjugated Linoleic Acid. network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	Ptgs2	Prostaglandin G/H synthase 2. (604 aa)
	Plin2	Perilipin; Belongs to the perilipin family. (432 aa)
	Hk2	Hexokinase-2. (704 aa)
	Aasdh	Acyl-CoA synthetase family member 4. (223 aa)
	Mtor	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
	I79_021198	Acetyl-CoA carboxylase 1. (231 aa)
	I79_021176	Perilipin; Belongs to the perilipin family. (518 aa)
	Bckdha	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (338 aa)
	Mapk3	Mitogen-activated protein kinase. (408 aa)
	Pnpla2	Patatin-like phospholipase domain-containing protein 2. (486 aa)
	I79_016908	Hormone-sensitive lipase. (326 aa)
	Napepld	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D. (236 aa)
	Rps6ka1	Ribosomal protein S6 kinase. (743 aa)
	Slc9a1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
	Adipoq	Adiponectin. (248 aa)
	Ins	Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
	Apoe	Apolipoprotein E. (313 aa)
	Akt2	Non-specific serine/threonine protein kinase. (200 aa)
	Igfbp3	Insulin-like growth factor-binding protein 3. (75 aa)
	Plin3	Perilipin; Belongs to the perilipin family. (440 aa)
	I79_008173	Perilipin; Belongs to the perilipin family. (419 aa)
	Plin4	Perilipin; Belongs to the perilipin family. (381 aa)
	Acss2	Acetyl-coenzyme A synthetase, cytoplasmic. (391 aa)
	I79_006999	Acetyl-CoA carboxylase 1. (1579 aa)
	Acss1	Acetyl-coenzyme A synthetase. (577 aa)
	Hkdc1	Putative hexokinase HKDC1. (925 aa)
	Hk1	Hexokinase-1. (917 aa)
	Rps6ka3	Non-specific serine/threonine protein kinase. (712 aa)
	Tjp1	Tight junction protein ZO-1. (762 aa)
	Slc16a7	Monocarboxylate transporter 2. (484 aa)
	Pkm	Pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
	Akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	Ddhd2	Phospholipase DDHD2. (697 aa)
	Hk3	Hexokinase-3. (867 aa)
	Lep	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	Src	Tyrosine-protein kinase. (536 aa)
	Fasn	Fatty acid synthase. (2503 aa)
	Akap12	A-kinase anchor protein 12. (837 aa)
	Adcy5	Adenylate cyclase type 5. (918 aa)
	Enah	Protein enabled-like. (391 aa)
	Acly	ATP-citrate synthase. (59 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aasdh	Acly	G3IFL0	G3IPP8	Acyl-CoA synthetase family member 4.	ATP-citrate synthase.	0.454
Aasdh	Acss1	G3IFL0	G3H6Z7	Acyl-CoA synthetase family member 4.	Acetyl-coenzyme A synthetase.	0.713
Aasdh	Acss2	G3IFL0	G3HAP6	Acyl-CoA synthetase family member 4.	Acetyl-coenzyme A synthetase, cytoplasmic.	0.564
Aasdh	Fasn	G3IFL0	G3GXD7	Acyl-CoA synthetase family member 4.	Fatty acid synthase.	0.979
Aasdh	I79_006999	G3IFL0	G3H9D1	Acyl-CoA synthetase family member 4.	Acetyl-CoA carboxylase 1.	0.526
Aasdh	I79_016908	G3IFL0	G3I0M0	Acyl-CoA synthetase family member 4.	Hormone-sensitive lipase.	0.635
Aasdh	I79_021198	G3IFL0	G3IC10	Acyl-CoA synthetase family member 4.	Acetyl-CoA carboxylase 1.	0.526
Aasdh	Napepld	G3IFL0	G3HYU9	Acyl-CoA synthetase family member 4.	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D.	0.405
Acly	Aasdh	G3IPP8	G3IFL0	ATP-citrate synthase.	Acyl-CoA synthetase family member 4.	0.454
Acly	Acss1	G3IPP8	G3H6Z7	ATP-citrate synthase.	Acetyl-coenzyme A synthetase.	0.506
Acly	Acss2	G3IPP8	G3HAP6	ATP-citrate synthase.	Acetyl-coenzyme A synthetase, cytoplasmic.	0.508
Acly	Bckdha	G3IPP8	G3IA13	ATP-citrate synthase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.510
Acly	Fasn	G3IPP8	G3GXD7	ATP-citrate synthase.	Fatty acid synthase.	0.978
Acss1	Aasdh	G3H6Z7	G3IFL0	Acetyl-coenzyme A synthetase.	Acyl-CoA synthetase family member 4.	0.713
Acss1	Acly	G3H6Z7	G3IPP8	Acetyl-coenzyme A synthetase.	ATP-citrate synthase.	0.506
Acss1	Acss2	G3H6Z7	G3HAP6	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase, cytoplasmic.	0.904
Acss1	Bckdha	G3H6Z7	G3IA13	Acetyl-coenzyme A synthetase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.460
Acss1	Fasn	G3H6Z7	G3GXD7	Acetyl-coenzyme A synthetase.	Fatty acid synthase.	0.526
Acss1	I79_006999	G3H6Z7	G3H9D1	Acetyl-coenzyme A synthetase.	Acetyl-CoA carboxylase 1.	0.513
Acss1	I79_021198	G3H6Z7	G3IC10	Acetyl-coenzyme A synthetase.	Acetyl-CoA carboxylase 1.	0.513